血浆脑钠肽评估心源性脑卒中预后的临床价值  

Clinical Significance of Plasma Brain Natriuretic Peptide in Evaluating the Prognosis of Cardiogenic Stroke

作　　者：邱雪 王文科 QIU Xue;WANG Wenke(Shuangqiao Hospital,Chaoyang District,Beijing 100024,China)

机构地区：[1]北京市朝阳区双桥医院,北京100024

出　　处：《中西医结合心脑血管病杂志》2022年第11期2062-2064,共3页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

摘　　要：目的探讨心源性脑卒中预后评估中血浆脑钠肽水平的临床意义。方法回顾性选取2018年6月—2019年6月北京市朝阳区双桥医院心源性脑卒中病人40例,依据入院即刻血浆脑钠肽水平分为低水平组(<200 ng/L)和高水平组(≥200 ng/L),每组20例。记录两组病人的性别、年龄、既往脑卒中发病史、发病后头颅CT检查结果。随访1年,记录两组大动脉粥样硬化、小动脉闭塞、再发脑栓塞及慢性阻塞性肺疾病、高血压、高脂血症、糖尿病、冠心病发生情况,脑梗死面积、1年复发率、1年生存率、1年死亡率情况。结果低水平组大动脉粥样硬化、小动脉闭塞、再发脑栓塞发生率均明显低于高水平组,差异均有统计学意义(P<0.05)。低水平组慢性阻塞性肺疾病、高血压、高脂血症、糖尿病、冠心病发生率均明显低于高水平组,差异均有统计学意义(P<0.05)。低水平组脑梗死面积小于高水平组,1年复发率、1年死亡率均明显低于高水平组,1年生存率高于高水平组,差异均有统计学意义(P<0.05)。结论血浆脑钠肽水平在心源性脑卒中预后评估中具有重要的临床意义。Objective To investigate the clinical significance of plasma brain natriuretic peptide level in the prognosis evaluation of cardiogenic stroke.Methods Forty patients with cardiogenic stroke from June 2018 to June 2019 in Shuangqiao Hospital,Chaoyang District,Beijing were retrospectively selected.According to the level of plasma natriuretic peptide at admission,they were divided into low level group(<200 ng/L)and high level group(≥200 ng/L),with 20 patients in each group.Gender,age,history of stroke,and CT results after the onset were recorded in two groups.The patients were followed up for 1 year,and the occurrence of large artery atherosclerosis,small artery occlusion,recurrent cerebral thrombosis,chronic obstructive pulmonary disease,hypertension,hyperlipidemia,diabetes,coronary heart disease,cerebral infarction area,1-year recurrence rate,1-year survival rate and 1-year mortality were analyzed.Results The incidence of large artery atherosclerosis,small artery occlusion and recurrent cerebral thrombosis in low level group were significantly lower than that in the high level group,the differences were statistically significant(P<0.05).The incidence of chronic obstructive pulmonary disease,hypertension,hyperlipidemia,diabetes,and coronary heart disease in low level group were significantly lower than that in the high level group,the differences were statistically significant(P<0.05).The cerebral infarction area in the low level group was smaller than that in the high level group,the difference was statistically significant(P<0.05),the 1-year recurrence rate and 1-year mortality rate of low level group were significantly lower than that in the high level group,the differences were statistically significant(P<0.05),and the 1-year survival rate was higher than that in the high level group,the difference was statistically significant(P<0.05).Conclusion The level of plasma brain natriuretic peptide is a important indication for the prognosis evaluation of cardiogenic stroke.

关 键 词：心源性脑卒中 血浆脑钠肽 预后 复发率 

分 类 号：R743.3[医药卫生—神经病学与精神病学]