低强度脉冲超声波应用于中重度慢性牙周炎治疗的临床效果研究  

Clinical effect of low-intensity pulsed ultrasound in the treatment of moderate to severe chronic periodontitis

作　　者：宁晓桥 刘湘 晋茹 叶国[1] NING Xiao-qiao;LIU Xiang;JIN Ru(Outpatient Department,Affiliated Stomatological Hospital of Chongqing Medical University,Chongqing 400000,China)

机构地区：[1]重庆医科大学附属口腔医院附三院门诊部,400000

出　　处：《中国实用医药》2022年第12期33-37,共5页China Practical Medicine

基　　金：重庆市卫生计生委医学研究项目(项目编号:2017ZDXM016)。

摘　　要：目的分别评估低强度脉冲超声波(LIPUS)辅助龈下刮治和根面平整术(SRP)以及引导性组织再生术(GTR)联合植骨术治疗中重度慢性牙周炎的效果。方法选取20例(20颗牙)中重度慢性牙周炎患者,按随机数字表法分为A组及B组,每组10例(10颗牙);另选取20例(20颗牙)具有GTR联合植骨术手术适应证的中重度慢性牙周炎患者,按随机数字表法分为C组及D组,每组10例(10颗牙)。A组采用SRP+常规口腔卫生维护治疗,B组采用SRP+LIPUS治疗,C组采用GTR联合植骨术+常规口腔卫生维护治疗,D组采用GTR联合植骨术+LIPUS治疗。比较A组与B组、C组与D组患牙不同时间节点牙周探诊深度(PD)、出血指数(BI)和临床附着水平(CAL)以及C组与D组患牙不同时间节点植骨区锥形束CT(CBCT)骨密度。结果术后4、8周,A组与B组PD和BI均低于本组基线,差异有统计学意义(P<0.05),表明A组与B组治疗对缓解患牙PD及BI情况均有一定效果;但A组与B组术后4、8周CAL与基线组内比较差异均无统计学意义(P>0.05)。术后8周,A组与B组PD明显小于术后4周,差异有统计学意义(P<0.05);但两组术后8周PD组间比较差异无统计学意义(P>0.05);B组术后8周BI明显低于术后4周,且B组低于A组,差异有统计学意义(P<0.05)。术后6个月,C组与D组PD、CAL、BI均低于本组基线,差异具有统计学意义(P<0.05);但C组与D组PD、CAL、BI组间比较差异无统计学意义(P>0.05)。术后即刻、3个月、6个月,C组CBCT骨密度分别为(113.05±52.54)、(152.27±23.54)、(303.69±72.41)HU;D组CBCT骨密度分别为(119.28±56.82)、(183.41±22.57)、(315.08±92.57)HU。术后3、6个月,C组与D组CBCT骨密度均高于本组术后即刻,且术后6个月高于本组术后3个月,差异有统计学意义(P<0.05)。术后3个月,D组CBCT骨密度高于C组,差异具有统计学意义(P<0.05);但术后6个月,C组与D组CBCT骨密度组间比较差异无统计学意义(P>0.05)。结论LIPUS辅助SRP或GTR联合植骨再�Objective To evaluate the effect of low-intensity pulsed ultrasound(LIPUS)assisted scaling and root planing(SRP)or guided tissue regeneration(GTR)combined with bone grafting in the treatment of moderate to severe chronic periodontitis respectively.Methods A total of 20 patients(20 teeth)with moderate to severe chronic periodontitis were divided into group A and group B according to the random numerical table,with 10 cases(10 teeth)in each group.Another 20 patients(20 teeth)with moderate to severe chronic periodontitis who had indications for GTR combined with bone grafting were selected and divided into group C and group D according to the random numerical table,with 10 cases(10 teeth)in each group.Group A was treated with SRP+conventional oral hygiene maintenance,group B was treated with SRP+LIPUS,group C was treated with GTR combined with bone grafting+conventional oral hygiene maintenance,and group D was treated with GTR combined with bone grafting+LIPUS.The periodontal probing depth(PD),bleeding index(BI)and clinical attachment level(CAL)at different time points of the teeth in group A and group B,group C and group D,and the bone density of cone beam CT(CBCT)at different time points of the implant area in group C and group D were compared.Results At 4 and 8 weeks postoperatively,PD and BI in group A and group B were lower than the baseline in this group,and the difference was statistically significant(P<0.05),indicating that treatment in group A and group B was effective in alleviating PD and BI in the affected teeth.However,there was no statistically significant difference between group A and group B in CAL at 4 and 8 weeks postoperatively compared with baseline within the group(P>0.05).At 8 weeks postoperatively,PD in group A and group B was significantly less than that at 4 weeks postoperatively,and the difference was statistically significant(P<0.05).However,there was no statistically significant difference between the two groups in comparison of PD at 8 weeks postoperatively(P>0.05).BI in group B at 8 we

关 键 词：低强度脉冲超声波 中重度慢性牙周炎 龈下刮治和根面平整术 引导性组织再生术 植骨术 

分 类 号：R781.42[医药卫生—口腔医学]