溃疡性结肠炎临床病理特点及鉴别诊断  

Clinicopathological features and differential diagnosis of ulcerative colitis

作　　者：苏晓路[1] 董弛[1] 张静[1] 毛杰[1] 郭继武[1] 王祥[1] Su Xiaolu;Dong Chi;Zhang Jing;Mao Jie;Guo Jiwu;Wang Xiang(Lanzhou University Second Hospital,lanzhou 730030,Gansu,China)

机构地区：[1]兰州大学第二医院,甘肃兰州730030

出　　处：《生物医学转化》2022年第2期66-74,共9页Biomedical transformation

基　　金：甘肃省重点研发计划项目(21YF5FA124)。

摘　　要：溃疡性结肠炎(Ulcerative Colitis,UC)是慢性炎症性肠病(Inflammatory Bowel Disease,IBD)的一种,病因和发病机制尚不完全明确,目前认为是多种致病因素相互作用的共同结果,主要包括环境、遗传、肠道微环境和免疫等因素,其中肠道免疫系统紊乱所致肠粘膜持续性慢性炎症在UC中发挥着重要作用。通过文献复习,并结合临床实际工作中所遇到的病例,本文系统论述了UC的临床流行病学特征、内镜、影像、实验室检查以及UC的治疗和预后,重点阐述UC的病理学形态和鉴别诊断。Ulcerative colitis(UC)is a chronic inflammatory bowel disease(IBD).The etiology and pathogenesis are not completely clear,and are currently considered to be the result of the interaction of multiple pathogenic factors.It mainly includes environmental,genetic,intestinal microenvironment and immune factors,among which chronic intestinal mucosa inflammation caused by intestinal immune system disorder plays an important role in UC.By reviewing the literature and combining with the cases in clinical practice,we systematically discusse the clinical epidemiological features,endoscopy,medical image,laboratory examination,treatment and prognosis of UC,focusing on the pathological morphology and differential diagnosis of UC.

关 键 词：溃疡性结肠炎 病理 内镜 影像 实验室检查 病理鉴别诊断 

分 类 号：R574.1[医药卫生—消化系统] R36[医药卫生—内科学] R447[医药卫生—临床医学]