缺陷型精神分裂症发病机制、诊断与治疗的研究进展  

Research progress of the pathogenesis,diagnosis and treatment of deficit schizophrenia

作　　者：田文豪 程哲[1] 陈雷音[1] 郭飞 杨世昌[1] Tian Wenhao;Cheng Zhe;Chen Leiyin;Guo Fei;Yang Shichang(Department of Psychiatry,the Second Affiliated Hospital of Xinxiang Medical University,Xinxiang 453002,China;Department of Pharmacy,the Second Affiliated Hospital of Xinxiang Medical University,Xinxiang 453002,China)

机构地区：[1]新乡医学院第二附属医院精神科,453002 [2]新乡医学院第二附属医院药学部,453002

出　　处：《神经疾病与精神卫生》2022年第6期414-419,共6页Journal of Neuroscience and Mental Health

基　　金：2019年度新乡市科技攻关计划项目(GG2019039)。

摘　　要：缺陷型精神分裂症是原发性精神分裂症的一个亚型,其主要临床特点为原发性、持续性的阴性症状。与非缺陷型精神分裂症相比,其起病年龄更早,认知障碍更严重,远期精神衰退更明显,疾病负担更重。现对国内外文献进行收集与分析,就缺陷型精神分裂症的病因与发病机制、诊断和治疗进行综述,以提高对该疾病的早期识别及加强干预。Deficit schizophrenia is a subtype of primary schizophrenia,whose main clinical features are primary,persistent negative symptoms.Compared with non-deficit schizophrenia,patients with deficit schizophrenia have earlier onset age,more severe cognitive disorders,more obvious long-term mental recession,and a heavier disease burden.Through the retrieval and analysis of the existing literature both in China and abroad,this paper reviews the pathogenesis,diagnosis,and therapy of deficit schizophrenia,in order to improve the early recognition of the disease and strengthen intervention.

关 键 词：缺陷型精神分裂症 发病机制 诊断 治疗 综述 

分 类 号：R749.3[医药卫生—神经病学与精神病学]