经颅交流电刺激在精神神经疾病中应用及作用机制的研究进展  

Research progress of application and mechanism of action of transcranial alternating current stimulation in neuropsychiatric diseases

作　　者：汪晓 张庆娥 Wang Xiao;Zhang Qing'e(Faculty of Psychiatry of Capital Medical University,Beijing Key Laboratory of Diagnosis and Treatment of Mental Diseases,National Clinical Medical Research Center for Mental Disorders,Beijing Anding Hospital,Capital Medical University,Beijing 100088,China)

机构地区：[1]首都医科大学附属北京安定医院国家精神心理疾病临床医学研究中心精神疾病诊断与治疗北京市重点实验室首都医科大学精神病学系,100088

出　　处：《神经疾病与精神卫生》2022年第6期444-447,共4页Journal of Neuroscience and Mental Health

基　　金：北京市教育委员会科技计划一般项目(KM202010025011);北京市科技计划(Z191100006619061)。

摘　　要：经颅交流电刺激是一种非侵入性脑电刺激方式,能够以正弦、双相交流电刺激皮质神经元,调节内源性脑振荡,并可诱导突触可塑性变化,帮助缓解抑郁、焦虑、妄想、痴呆等症状。现通过综述其在抑郁症、精神分裂症等疾病中的临床应用及作用机制,了解目前研究的进展及不足,为今后的临床应用起到部分提示作用。Transcranial alternating current stimulation is a non-invasive form of brain stimulation that can use sinusoidal and bipolar alternating currents to stimulate cortical neurons,regulate endogenous brain oscillations,and induce synaptic plasticity changes,help to relieve symptoms such as depression,anxiety,delusions,and dementia.This article reviews its clinical application and mechanism in depression,schizophrenia,and other diseases to help us understand the progress and deficiency of current research,and provide some hints for future clinical application.

关 键 词：经颅交流电刺激 精神疾病 治疗 作用机制 综述 

分 类 号：R749[医药卫生—神经病学与精神病学]