腹腔镜下子宫肌瘤剔除术治疗子宫肌瘤的疗效及对免疫功能的影响分析  

Efficacy of laparoscopic myomectomy in the treatment of uterine myoma and its influence on immune function

作　　者：金盼盼 JIN Pan-pan(Dalian Women and Children's Medical Center,Dalian 116037,China)

机构地区：[1]大连市妇女儿童医疗中心,116037

出　　处：《中国现代药物应用》2022年第9期47-50,共4页Chinese Journal of Modern Drug Application

摘　　要：目的探讨腹腔镜下子宫肌瘤剔除术治疗子宫肌瘤的疗效,分析手术对于患者免疫功能的影响。方法90例子宫肌瘤患者作为研究对象,随机分为观察组和对照组,各45例。观察组患者采用腹腔镜下子宫肌瘤剔除术治疗,对照组患者采用开腹手术治疗。比较两组患者术后恢复情况、手术前后免疫功能指标水平、术后并发症发生情况。结果观察组患者的肛门排气恢复时间(18.37±2.61)h、下床活动时间(9.85±1.74)h、住院时间(7.04±2.16)d均短于对照组的(23.85±3.45)h、(15.63±2.07)h、(9.85±2.74)d,差异具有统计学意义(P<0.05)。术前,两组患者的CD3^(+)、CD4^(+)比较差异无统计学意义(P>0.05);术后,观察组患者的CD3^(+)(46.13±2.92)%、CD4^(+)(37.04±2.61)%均高于对照组的(41.59±3.67)%、(33.85±3.02)%,差异具有统计学意义(P<0.05)。观察组患者的术后并发症发生率4.44%低于对照组的20.00%,差异具有统计学意义(χ^(2)=5.075,P<0.05)。结论腹腔镜下子宫肌瘤剔除术治疗子宫肌瘤,可以获得良好的疗效,且对于患者免疫功能的影响较小,有利于患者术后快速、良好的恢复。Objective To discuss the efficacy of laparoscopic myomectomy in the treatment of uterine myoma and analyze its influence on immune function of patients.Methods A total of 90 patients with uterine myoma were selected as the research subjects and were randomly divided into the observation group and the control group,with 45 cases in each group.Patients in the observation group were treated with laparoscopic myomectomy,and patients in the control group were treated with open surgery.The postoperative recovery,immune function index levels before and after surgery,and postoperative complications were compared between the two groups.Results The recovery time of anal exhaust(18.37±2.61)h,the off-bed activity time(9.85±1.74)h,and the hospitalization time(7.04±2.16)d in the observation group were all shorter than(23.85±3.45)h,(15.63±2.07)h,and(9.85±2.74)d in the control group,and the difference was statistically significant(P<0.05).Before surgery,there was no statistically significant difference in CD3^(+)and CD4^(+)between the two groups(P>0.05).After surgery,the CD3^(+)(46.13±2.92)%and CD4^(+)(37.04±2.61)%of the observation group were higher than(41.59±3.67)%and(33.85±3.02)%of the control group,and the differences were statistically significant(P<0.05).The postoperative complication rate 4.44%in the observation group was lower than 20.00%in the control group,and the difference was statistically significant(χ^(2)=5.075,P<0.05).Conclusion Laparoscopic myomectomy can achieve good efficacy in the treatment of uterine myoma,and has little impact on the patient's immune function,which is conducive to the rapid and good recovery of patients after surgery.

关 键 词：腹腔镜下子宫肌瘤剔除术 子宫肌瘤 疗效 免疫功能 

分 类 号：R737.33[医药卫生—肿瘤]