2009—2018年湖南省肿瘤登记地区女性乳腺癌发病与死亡趋势分析  

Trend Analysis of Incidence and Mortality of Female Breast Cancer in Hunan Cancer Registration Areas from 2009 to 2018

作　　者：邹艳花 廖先珍 许可葵 肖海帆 胡莹云 石朝晖 李灿 曹世钰 郭佳 王石玉 李娜 颜仕鹏 ZOU Yan-hua;LIAO Xian-zhen;XU Ke-kui;XIAO Hai-fan;HU Ying-yun;SHI Zhao-hui;LI Can;CAO Shi-yu;GUO Jia;WANG Shi-yu;LI Na;YAN Shi-peng(Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine,Central South University/Hunan Cancer Prevention and Control Office,Changsha 410013,China)

机构地区：[1]湖南省肿瘤医院/中南大学湘雅医学院附属肿瘤医院/湖南省肿瘤防治研究办公室,湖南长沙410013

出　　处：《中国肿瘤》2022年第5期341-347,共7页China Cancer

摘　　要：[目的]分析湖南省肿瘤登记地区2009—2018年女性乳腺癌的发病与死亡情况。[方法]收集2009—2018年湖南省32个肿瘤登记点上报的女性乳腺癌发病与死亡数据,按照地区计算湖南省女性乳腺癌的发病(死亡)率、中标发病(死亡)率,年龄别发病(死亡)率、0~74岁累积发病(死亡)率、35~64岁截缩发病(死亡)率和年度变化百分比(annual percentage change,APC)等指标。[结果]2009—2018年湖南省肿瘤登记地区女性乳腺癌发病率为31.99/10万,0~74岁累积发病率为2.83%,35~64岁截缩发病率56.63/10万,城市地区以上三项指标分别为42.72/10万、4.07%、71.36/10万,农村地区以上三项指标分别为26.38/10万、2.20%、48.81/10万。2009—2018年湖南省肿瘤登记地区女性乳腺癌死亡率为8.86/10万,0~74岁累积死亡率为1.00%,35~64岁截缩死亡率13.49/10万,城市地区以上三项指标分别为11.73/10万、1.43%、16.86/10万,农村地区以上三项指标分别为7.36/10万、0.78%、11.69/10万。2009—2018年湖南省肿瘤登记地区女性乳腺癌中标发病率、0~74岁累积发病率、35~64岁截缩发病率呈上升趋势,且均有统计学意义(P均<0.05),APC依次为4.1%、4.9%、4.3%。趋势变化均在2011年出现一个拐点,2009—2011年的趋势变化无统计学意义。2009—2018年湖南省肿瘤登记地区女性乳腺癌中标死亡率、0~74岁累积死亡率、35~64岁截缩死亡率较为稳定,趋势变化无统计学意义。趋势均在2011年出现一个拐点,2011—2018年趋势变化均有统计学意义(P均<0.05)。2009—2018年湖南省肿瘤登记地区女性乳腺癌年龄别发病率峰值出现在50~54岁年龄组,年龄别死亡率呈持续增长趋势。[结论]湖南省肿瘤登记地区女性乳腺癌发病率呈明显逐年增长趋势,死亡率也有上升趋势,应加强对女性乳腺癌的防治。[Purpose]To analyze the trend of incidence and mortality of female breast cancer in Hunan cancer registration areas from 2009 to 2018.[Methods]The new cases and deaths data of female breast cancer were collected from 32 cancer registries of Hunan Province.The crude incidence/mortality rate,age-standardized incidence/mortality rate by Chinese standard population(ASIRC/ASMRC),age-specific incidence/mortality rate,the cumulative incidence/mortality rate(0~74 years old),the truncated incidence/mortality rate(35~64 years old),annual percentage change(APC)were calculated by stratification of areas.[Results]The average crude incidence rate,the cumulative incidence rate(0~74 years old)and the truncated incidence rate(35~64 years old)of female breast cancer were 31.99/10~5,2.83%,and 56.63/10~5,respectively in Hunan cancer registration areas from 2009 to 2018.These indicators were 42.72/10~5,4.07%and 71.36/10~5in urban areas;and 26.38/10~5,2.20%and 48.81/10~5in rural areas,respectively.The ASIRC,the cumulative incidence rate(0~74 years old)and the truncated incidence rate(35~64 years old)of female breast cancer from 2009 to 2018 showed a significantly increasing trend with the APC of 4.1%,4.9%and 4.3%,respectively(all P<0.05).The trend of these indicators showed a turning point in2011,and the trend changes from 2009 to 2011 were not statistically significant.The crude mortality rate,the cumulative mortality rate(0~74 years old)and the truncated mortality rate(35~64years old)of female breast cancer were 8.86/10~5,1.00%and 13.49/10~5,respectively in Hunan cancer registration areas from 2009 to 2018.And the above three indicators were 11.73/10~5,1.43%and 16.86/10~5in urban areas,and 7.36/10~5,0.78%and 11.69/10~5in rural areas,respectively.The ASMRC,the cumulative mortality rate(0~74 years old)and the truncated mortality rate(35~64 years old)of female breast cancer were relatively stable(P>0.05).The trend showed a turning point in 2011,and from 2011 to 2018 the changes were statistically significant(all P<0.05).The age-specifi

关 键 词：肿瘤登记 女性乳腺癌 发病率 死亡率 湖南 

分 类 号：R73-31[医药卫生—肿瘤]