视觉词语识别任务下左右脑功能网络局部形态的分化  

Local Morphological Differentiation Between Left and Right Functional Brain Network Under Visual Word Recognition Task

作　　者：张笑非 杨阳[3,4] 钟宁 ZHANG Xiaofei;YANG Yang;ZHONG Ning(Faculty of Information Technology,Beijing University of Technology,Beijing 100124,China;School of Computer,Jiangsu University of Science and Technology,Zhenjiang 212003,Jiangsu,China;Beijing Key Laboratory of MRI and Brain Informatics,Beijing 100124,China;School of Humanities and Social Sciences,Beijing Forest University,Beijing 100089,China;Department of Life Science and Informatics,Maebashi Institute of Technology,Maebashi 371-0816,Gunma,Japan)

机构地区：[1]北京工业大学信息学部,北京100124 [2]江苏科技大学计算机学院,江苏镇江212003 [3]磁共振成像脑信息学北京市重点实验室,北京100124 [4]北京林业大学人文社会科学学院,北京100089 [5]前桥工科大学生命科学与信息学系,群马前桥371-0816,日本

出　　处：《北京工业大学学报》2022年第7期773-782,共10页Journal of Beijing University of Technology

基　　金：国家自然科学基金资助项目(61420106005);北京市自然科学基金资助项目(4182005)。

摘　　要：为研究任务态下视觉词语识别时左右脑功能网络之间的拓扑形态差异,使用OpenfMRI开放项目“词语与对象处理”的45名被试tfMRI数据,分别构造单词条件和辅音字符串条件下基于解剖学脑图自动解剖标记(automated anatomical labelling, AAL)的左右脑功能网络,对2个半脑的度中心性、全局效率、聚类系数和局部效率进行统计对比,并考察AAL的兴趣点(region of interest, ROI)与功能脑图Willard-499语言网络的关系. 2种实验条件下左右脑网络指标在稀疏度定义域差异均有统计学意义,其中辅音字符串实验条件下4个指标统计学差异占比分别为0、0、0、0,单词条件下分别为0、5%、0、44%,单词条件下聚类系数与局部效率差异占比存在反差.左右脑功能网络在进行单词识别时存在局部形态的分化.To study the topological differences between the left and right functional brain networks during visual word recognition in task mode,with the 45 subjects'tfMRI data from the OpenfMRI project database of Word and Object Processing,the left-and-right functional brain networks under the conditions of words and consonant strings were constructed based on the anatomical brain atlas automated anatomical labelling(AAL),respectively.The degree centrality,global efficiency,clustering coefficient and local efficiency of the two hemispheres were statistically compared,and the relationship between regions of interest(ROIs)of AAL and the language network of functional brain atlas Willard-499 was investigated.Significant statistical differences were identified between the left and right brain network indexes in the sparsity domain under the two experimental conditions.The four significant differences of the indexes were 0,0,0 and 0 under the consonant string experiment condition,and 0,5%,0,and 44%under the word experiment condition,respectively.The sharp contrast on the percentage of significant differences between the clustering coefficient and the local efficiency was identified under the word experiment condition.The left and right functional brain networks could be differentiated in local morphology during the visual word recognition.

关 键 词：视觉词语识别 任务诱发功能磁共振成像 脑功能网络 局部形态 视觉词形区 大脑图谱对比 

分 类 号：O157[理学—数学] B841[理学—基础数学]