蛋白质自组装研究进展  

Progress on Protein Self-assembly

作　　者：赵广华[1] 张晓荣 ZHAO Guanghua;ZHANG Xiaorong(College of Food Science and Nutritional Engineering,China Agricultural University,Beijing 100083,China)

机构地区：[1]中国农业大学食品科学与营养工程学院,北京100083

出　　处：《山西大学学报（自然科学版）》2022年第3期744-759,共16页Journal of Shanxi University(Natural Science Edition)

基　　金：国家自然科学基金(31730069)。

摘　　要：在生物体内,大多数蛋白质通过非共价相互作用以有序组织的自组装形式发挥作用。受大自然启发,人工设计蛋白质自组装正如火如荼的展开。近二十年来,蛋白质自组装领域快速发展,成功构建了各式各样,具有广泛结构和功能特性的蛋白质组装体。文章总结了用于调控蛋白质自组装的设计策略和工具,以及构建蛋白质组装体的最新进展,并描述了这些组装体的自然属性和功能。In organisms,most proteins function in the form of ordered self-assembly through noncovalent interactions.Inspired by nature,artificial protein self-assembly is in full swing.In the past two decades,the field of protein self-assembly has developed rapidly,and a variety of protein assemblies with extensive structural and functional properties have been successfully constructed.This review outlines the design strategies and tools that have been devised for controlling protein self-assembly,and the diverse structures of artificial protein assemblies,and the emergent properties and functions of these assemblies.

关 键 词：生物大分子 蛋白质 自组装 

分 类 号：O436[机械工程—光学工程]