Severe IgA vasculitis with features of remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome in a 60‐year‐old male treated with plasmapheresis  

作　　者：Shawn Mathew Rohan Goyal Nealansh Gupta Rauno Joks 

机构地区：[1]Internal Medicine,Ringgold Standard Institution,SUNY Downstate Health Sciences University,Brooklyn,New York,USA [2]SUNY Downstate Medical Center College of Medicine,Ringgold Standard Institution,Brooklyn,New York,USA [3]Allergy and Immunology,Center for Allergy and Asthma Research,SUNY Downstate Health Sciences University,Brooklyn,New York,USA

出　　处：《Rheumatology & Autoimmunity》2022年第2期98-101,共4页风湿病与自身免疫（英文）

基　　金：This study is supported by SUNY Downstate Health Sciences University.

摘　　要：Objective:To explore a possible association between systemic immunoglobulin A(IgA)vasculitis and RS3PE syndrome and to investigate specific treatment regimens for adults who present with IgA vasculitis with renal involvement.Methods:The patient was treated with plasmapheresis and fresh frozen plasma(FFP)every other day with 1g methylprednisolone daily for three days followed by oral prednisone taper.Mycophenolate mofetil twice daily and trimethoprim‐sulfamethoxazole for Pneumocystis jirovecii prophylaxis was started.In total the patient received two cycles of plasmapheresis and fresh frozen plasma.Results:The patient's renal function drastically improved with resolution of both abdominal pain and nausea.Conclusion:We illustrate a possible association between systemic IgA vasculitis and RS3PE syndrome,and this case demonstrates IgA vasculitis with renal involvement that acutely resolved with high‐dose glucocorticoids and plasmapheresis.Additionally,our specific treatment regimen can be a potential standard of care for adults who present with IgA vasculitis with renal involvement.

关 键 词：IgA vasculitis PLASMAPHERESIS RS3PE syndrome 

分 类 号：R73[医药卫生—肿瘤]