双相障碍住院患者季节性特征分析  

Seasonal characteristics of inpatients with bipolar disorder.

作　　者：孙倩 任艳萍[1,2] 罗炯[1,2] 王雯[1,2] 王雪[1,2] 王丹[1,2] 姜玮[1,2] SUN Qian;REN Yanping;LUO Jiong;WANG Wen;WANG Xue;WANG Dan;JIANG Wei(The National Clinical Research Center for Mental Disorders&Beijing Key Laboratory of Mental Disorders,Beijing Anding Hospital,Capital Medical University,Beijing 100088,China;Advanced Innovation Center for Human Brain Protection,Capital Medical University,Beijing 100069,China)

机构地区：[1]首都医科大学附属北京安定医院,精神疾病诊断与治疗重点实验室,国家精神心理疾病临床医学研究中心,北京100088 [2]人脑保护高精尖创新中心,首都医科大学

出　　处：《中国神经精神疾病杂志》2022年第3期144-147,共4页Chinese Journal of Nervous and Mental Diseases

基　　金：国家重点研发计划“重大慢性非传染性疾病防控研究”重点专项(编号:2017YFC1311101)。

摘　　要：目的探索双相障碍住院患者的季节性特征,为个性化综合治疗提供证据支持。方法采用横断面调查,通过北京安定医院病历数据库,回顾性纳入双相障碍患者,收集患者的人口学资料及临床特征,根据患者入院的季节进行统计分析。结果共纳入患者8409例,春季入院2311例(27.5%),夏季入院2090例(24.9%),秋季入院2028例(24.1%),冬季入院1980例(23.5%)。各季节入院组间比较显示年龄、住院时长、是否伴自伤自杀差异具有统计学意义(P<0.05)。春季组、秋季组年龄分别低于冬季组[(33.0±12.1)岁vs.(33.0±11.9)岁vs.(34.1±12.3)岁,P<0.05];住院时长秋季组、夏季组长于冬季组[(32.1±20.3)d vs.(31.6±17.2)d vs.(29.7±21.8)d,P<0.05],秋季组长于春季组[(30.4±15.5)d,P<0.05];夏季组伴自伤自杀高于秋季组(48.4%vs.43.6%,P<0.05)。结论在双相障碍住院患者中,春季、秋季入院患者年龄比冬季入院患者低,秋季入院患者住院时长比冬季、春季入院患者长,夏季入院患者住院时长比冬季入院患者长,夏季入院患者伴自伤自杀的比例高于秋季入院患者。因此可以针对患者的季节性特征进行个性化治疗。Objective evidence for personalized comprehensive treatment.MethodsA retrospective,cross-sectional survey were conducted on patients with bipolar disorder in the medical records database of Beijing Anding Hospital.The demographic data and clinical characteristics of the patients were collected and statistically analyzed according to the season of admission.Results autumn(24.1%),and 1980 in winter(23.5%).The comparison among admission groups in different seasons showed that there were significant differences in age,length of stay,and with self-injury or suicide(P<0.05).The age of spring group and autumn group were lower than that of winter group[(33.0±12.1)years vs.(33.0±11.9)years vs.(34.1±12.3)years,P<0.05].The length of hospitalization in autumn group and summer group was longer than that in winter group[(32.1±20.3)d vs.(31.6±17.2)d vs.(29.7±21.8)d,P<0.05].And the length of hospitalization in autumn group was longer than that in spring group[(30.4±15.5)d,P<0.05].The rate of patients with self injury or suicide in summer group was higher than that in autumn group(48.4%vs.43.6%,P<0.05).Conclusion lower in spring and autumn than in winter.The length of hospitalization in autumn is longer than that in winter and spring,and the length of hospitalization in summer is longer than that in winter.The rate of patients with self-injury or suicide in summer is higher than that in autumn.Therefore,personalized treatment should be adopted according to the seasonal characteristics of patients.

关 键 词：双相障碍 住院患者 季节性 特征 临床 自杀自伤 

分 类 号：R749.4[医药卫生—神经病学与精神病学]