非酮症高血糖偏侧舞蹈症5例临床特点分析  

Clinical features of hemichorea associated with nonketotic hyperglycemia: An analysis of 5 cases

作　　者：唐艳丹 彭永 甘棋心 陆芝兰[3] 李为 崔俐莉 TANG Yan-Dan;PENG Yong;GAN Qi-Xin;LU Zhi-Lan;LI Wei;CUI Li-Li(Department of Neurology,Third affiliated hospital,Hunan University of Chinese Medicine,Zhuzhou,Hunan 412000,China;Department of Neurology,Affiliated First Hospital of Hunan Traditional Chinese Medical College,Zhuzhou,Hunan 412000,China;Department of Endocrinology,Affiliated First Hospital of Hunan Traditional Chinese Medical College,Zhuzhou,Hunan 412000,China;Department of Radiology,Affiliated First Hospital of Hunan Traditional Chinese Medical College,Zhuzhou,Hunan 412000,China)

机构地区：[1]湖南中医药大学第三附属医院神经内科,湖南株洲412000 [2]湖南中医药高等专科学校附属第一医院神经内科,湖南株洲412003 [3]湖南中医药高等专科学校附属第一医院内分泌科,湖南株洲412000 [4]湖南中医药高等专科学校附属第一医院放射科,湖南株洲412000

出　　处：《国际神经病学神经外科学杂志》2022年第2期65-69,共5页Journal of International Neurology and Neurosurgery

基　　金：湖南省中医药管理局重点课题(201915);湖南省自然科学基金(2018JJ6043);湖南省卫计委课题(B20180815);湖南中医药高等专科学校附属第一医院优秀科研创新团队(B2021-003)。

摘　　要：由糖尿病引起的非酮症高血糖偏侧舞蹈症(HC-NH)临床较为罕见。该文报道了5例HC-NH患者,均为老年女性,平均年龄70岁,有糖尿病史,发病至入院时间4~30 d,糖化血红蛋白7.6%~17.5%。所有患者均自一侧肢体起病;1例患者头颅CT表现为发病对侧基底节区稍高密度影;3例患者MRI提示基底节区(单侧或双侧基底节)高信号,病灶呈团片状或斑点状;1例无MRI异常表现。所有患者在降糖或增加抗多巴胺能类药物治疗后症状缓解,预后良好。Hemichorea associated with nonketotic hyperglycemia(HC-NH) caused by diabetes is relatively rare in clinical practice.This article reported 5 cases of HC-NH patients.All patients were elderly women,with an average age of 70 years and a history of diabetes.The time from disease onset to admission ranged from 4 to 30 days,and the level of glycosylated hemoglobin ranged from 7.6% to 17.5%.All patients had disease onset from one limb;1 patient had slightly high-density shadow in the contralateral basal ganglia area on head CT scan;3 patients’ showed high signal intensity in the basal ganglia(unilateral or bilateral) on MRI,and the lesions were mass flakes or spots;1 patient had no abnormal manifestation on MRI.All patients achieved the relief of symptoms and had a good prognosis after hypoglycemic therapy or the addition of anti-dopaminergic drugs.

关 键 词：舞蹈症 非酮症 高血糖症 磁共振成像 诊断 

分 类 号：R742.2[医药卫生—神经病学与精神病学]