肉芽肿性小叶性乳腺炎与乳腺浸润性小叶癌超声声像图特征对比研究  

Comparison of ultrasonographic features in the granulomatous lobular mastitis and infiltrating lobular carcinoma of the breast

作　　者：刘艳超 孝梦甦[1] 吕珂[1] 吴倩岚 刘郭坤 LIU Yanchao;XIAO Mengsu;LYU Ke;WU Qianlan;LIU Guokun(Department of Ultrasound,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Department of Ultrasound,The Central Hospital of Handan,Handan 056000,Hebei Province,China;Department of Pathology,The First People’s Hospital of Handan,Handan 056000,Hebei Province,China;Department of CT/MRI,The Central Hospital of Handan,Handan 056000,Hebei Province,China)

机构地区：[1]中国医学科学院北京协和医学院,北京协和医院超声科,北京100730 [2]邯郸市中心医院超声医学科,河北邯郸056000 [3]邯郸市第一人民医院病理科,河北邯郸056000 [4]邯郸市中心医院CT/MRI室,河北邯郸056000

出　　处：《肿瘤影像学》2022年第3期243-248,共6页Oncoradiology

基　　金：国家自然科学基金(81873902);中国医学科学院医学与健康科技创新工程(2016-I2M-3-005);中国医学科学院临床与转化医学研究(2020-I2M-C&T-B-039)。

摘　　要：目的:总结并对比肉芽肿性小叶性乳腺炎(granulomatous lobular mastitis,GLM)与乳腺浸润性小叶癌(infiltrating lobular carcinoma of the breast,ILC)的超声声像图特征,以期提高对两者的鉴别诊断。方法:回顾并分析北京协和医院28个GLM病灶及58个ILC病灶超声图像,对比分析两组患者的临床资料及超声声像图表现,包括病灶形态、纵横比、边界、周边晕环、内部导管扩张、液化区、钙化等。结果:两组病灶在发病年龄、红肿热痛等临床表现,以及超声显示的形态、内部导管扩张、液化区及钙化等方面差异均有统计学意义(P<0.05)。结论:GLM相较于ILC病灶内更易出现液化区、导管扩张、血流丰富等表现,综合分析超声与临床表现有助于提高对两者的鉴别诊断。Objective: To summarize and compare the ultrasonographic features of granulomatous lobular mastitis(GLM) and infiltrating lobular carcinoma of the breast(ILC) for improving the differential diagnosis of them. Methods: The ultrasound images of 28 GLM lesions and 58 ILC lesions in Peking Union Medical College Hospital were retrospectively analyzed. The clinical data and ultrasound images of the lesions were compared and analyzed between the two groups, including morphology, aspect ratio,boundary, halo, ductal dilatation, fluid area, calcification. Results: There were significant differences between the two groups in clinical manifestations(age of onset, redness, swelling, heat and pain, etc.) and ultrasonographic features(morphology, internal catheter expansion, liquefaction area and calcification)(P<0.05). Conclusion: Compared with ILC, GLM is more likely to appear with liquid area, duct dilatation, rich blood flow. Comprehensive analysis of ultrasound imaging and clinical manifestations helps to improve the differential diagnosis of them.

关 键 词：肉芽肿性小叶性乳腺炎 乳腺浸润性小叶癌 超声 

分 类 号：R737.9[医药卫生—肿瘤] R445.1[医药卫生—临床医学]