额面部丛状神经鞘瘤1例  

Plexiform schwannoma on the frontal region:a case report

作　　者：张秀文 于炳洋[1] 孙磊 ZHANG Xiuwen;YU Bingyang;SUN Lei(Weihai Municipal Hospital,Weihai 264200,China)

机构地区：[1]威海市立医院,山东威海264200

出　　处：《皮肤性病诊疗学杂志》2022年第3期257-259,共3页Journal of Diagnosis and Therapy on Dermato-venereology

摘　　要：报告额面部丛状神经鞘瘤1例。患者女,48岁,因“额面部左侧肿物17年,左眉弓皮下肿物3年”就诊。皮肤专科检查:额面部左侧见一约8 mm×6 mm×3 mm大小黄红色类圆形结节,隆起于皮面,表面光滑,质地韧,无压痛。左眉弓上方皮下扪及一约9 mm×8 mm×4 mm大小的结节,质地韧,轻度压痛,活动度可。两处皮损组织病理均为:真皮中下层内可见多个由梭形细胞组成的肿瘤团块,呈结节状,结节间被透明疏松的纤维结缔组织所分隔。免疫组化结果:S-100(+++),Vimentin(+),SMA(-),CD34(-),Ki-67(5%+)。诊断为丛状神经鞘瘤。予以手术切除,随访3年未复发。A case of frontal plexiform schwannoma is reported.A 48-year-old female presented with a 17-year history of a mass on the left frontal region and a 3-year history of a tumor on the left eyebrow arch.Dermatological examination showed an about 8 mm×6 mm×3 mm yellow-red round nodule on the left frontal region.The nodule was firm without tenderness.A subcutaneous mobile nodule in size of about 9 mm×8 mm×4 mm was palpated above the left eyebrow arch,with a firm texture and mild tenderness.The histopathology of both lesions showed multiple tumor masses composed of spindle cells in the middle and lower dermis.Tumor masses were nodular,separated by thin fibrous connective tissue.Immunohistochemistry showed S-100(+++),Vimentin(+),SMA(-),CD34(-),and Ki-67(5%+).A plexiform schwannoma was diagnosed.Surgical resection was performed,and no recurrence was found during a 3-year follow-up.

关 键 词：丛状 神经鞘瘤 额面部 

分 类 号：R73[医药卫生—肿瘤]