广州市初中女生监护人对人乳头瘤病毒(HPV)疫苗接种意愿及影响因素研究  

Study on HPV vaccination willingness of junior middle school girls′guardians and factors in Guangzhou

作　　者：云雪霞[1] 王大虎[1] 谭慧峰[1] 倪莉红[1] 钟美玲 陈清[2] YUN Xue-xia;WANG Da-hu;TAN Hui-feng;NI Li-hong;ZHONG Mei-ling;CHEN Qing(Guangzhou Center for Disease Control and Prevention,Guandong 510440,China;不详)

机构地区：[1]广州市疾病预防控制中心,广东510440 [2]南方医科大学

出　　处：《医学动物防制》2022年第7期663-666,共4页Journal of Medical Pest Control

基　　金：广东省财政厅关于下达2021年第二批中央财政基本公共卫生服务等5项资金项目(粤财社[2021]103号);广东省财政厅关于提前下达2022年中央财政基本公共卫生服务补助资金的通知(粤财社[2021]314号);广州市科技计划资金资助项目(201904010025)。

摘　　要：目的掌握广州市初中女生监护人对人乳头瘤病毒(human papilloma virus,HPV)疫苗接种意愿及影响因素,为广州市初中女生HPV疫苗免疫接种策略的制定提供参考和依据。方法采用单纯随机抽样的方法对广州市12~14岁初中女生监护人进行问卷调查,对所得数据进行统计分析,采用Logistic回归方法分析影响广州市初中女生监护人HPV疫苗接种意愿的因素。结果共回收有效问卷7391份,90.22%的监护人愿意为孩子接种HPV疫苗,9.78%的监护人不愿接种。不愿接种的主要原因为:担心影响孩子生长发育(42.19%);担心疫苗安全性(41.77%);孩子年纪太小没必要接种(39.70%);对疫苗不了解(36.65%);疫苗的效果未知(31.67%)等。如果广州市开展国产2价HPV疫苗免费接种项目,74.28%的监护人表示愿意接种;3.83%的监护人表示不愿意接种;18.48%的监护人表示学校集体组织即前往接种;3.41%的监护人暂时不确定。农村及城市监护人接种意愿差异无统计学意义(χ^(2)=0.53,P>0.05)。多因素Logistic回归分析结果显示:低学历及低收入是影响疫苗接种意愿的主要因素。结论加强对人群HPV疫苗接种知识的健康教育,消除对接种疫苗的顾虑;推进免费接种策略,推动适龄人群尽早接种疫苗,增强人群接种意识,提高HPV疫苗接种率,从而达到大幅度降低宫颈癌发病率、保护女性健康的目标。Objective To master human papilloma virus(HPV)vaccination willingness and factors of junior middle school girls′guardians in Guangzhou,and to provide reference and basis for HPV immune strategy making of junior middle school girls in Guangzhou.Methods Questionnaire survey on 12-14 junior middle school girls′guardians by simplicity random sampling.The survey data were statistically analyzed,and the factor of junior middle school girls guardian′s HPV vaccination willingness were statistically analyzed by Logistic regression method.Results A total of 7391 effective questionnaires were received,90.22%guardians showed the willingness to inoculate HPV vaccine for their children,and 9.78%of them declined to do.The primary reason of unwillingness were as follows:worries about the influences of HPV vaccine on the growth and development of children(42.19%);concerns on the safety of HPV vaccine(41.77%);no necessity to inoculate because of excessive young age of children(39.70%);not familiarity with HPV vaccine(36.65%);unknown effects of HPV vaccine(31.67%),etc.74.28%guardian showed their desires to inoculate were established if the project was implemented free of charge of 2 value homegrown HPV vaccine in Guangzhou;3.83%guardians showed they didn′t want to inoculate;18.48%guardians showed they desired to inoculat if collective organization by school;3.41%guardians showed the indetermination for the moment.No significant difference was found between city and countryside(χ^(2)=0.53,P>0.05).Multi-factor Logistic regression analysis showed that low education background and low income were the major factors of vaccination willingness.Conclusion Health education about HPV vaccination knowledge should be strengthened to eliminate the scruple over vaccine.It is necessary to promote free vaccination strategy and the vaccination work of the right age group as early as possible,strengthen inoculate consciousness of group and increase vaccination rates,thereby significantly achieving the target of reducing the morbidity of cer

关 键 词：人乳头瘤病毒 疫苗接种 初中生 监护人 接种意愿 影响因素 

分 类 号：R186[医药卫生—流行病学]