Lower lip recurrent keratoacanthoma:A case report  

作　　者：Xian-Guang Liu Xing-Guang Liu Cai-Jiao Wang Han-Xi Wang Xu-Xia Wang 

机构地区：[1]Department of Oral and Maxillofacial Surgery,Shandong University,Jinan 250100,Shandong Province,China [2]Department of Oral Pathology,Shandong University,Jinan 250100,Shandong Province,China

出　　处：《World Journal of Clinical Cases》2022年第20期6960-6965,共6页世界临床病例杂志

摘　　要：BACKGROUND This paper introduces a case of recurrent keratoacanthoma(KA).KA is a selfhealing disease.Recurrence after surgical resection is rare.In this case,the local application of retinoic acid ointment after the second operation achieved a good prognosis after 2 years of follow-up.CASE SUMMARY A 76-year-old male patient was admitted to the hospital for"lower lip rupture and scab for 3 mo".Treatment:A rectangular incision was made in the healthy tissue about 3 mm outside the periphery of the lower lip mass,and a modified Bernard sliding flap was designed to completely remove the mass.Pathology showed(lower lip)KA.When the patient returned 6 mo after surgery,the middle mucosa of the lower lip had a bulge with a diameter of about 0.5 cm.The boundary was still clear,the surface was ulcerated.A recurrence of lower lip KA was suspected and a fan-shaped incision was performed in the healthy tissue about 5 mm outside the lesion to completely resect.Pathological showed lower lip KA had recurred.Topical application of tretinoin cream was applied once a day for 3 mo.The lower lip wounds were clean at the 2-year postoperative follow-up and the mucosa was normal.CONCLUSION Adjuvant retinoic acid treatment after KA surgical resection can achieve good results.

关 键 词：KERATOACANTHOMA Lower lip Squamous cell carcinoma Clinical features RECURRENCE Case report 

分 类 号：R739.8[医药卫生—肿瘤]