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作 者:Shu Li Li-Na Chen Lin Zhong
机构地区:[1]Department of Pediatric Pulmonology and Immunology,West China Second University Hospital of Sichuan University,Chengdu 610066,Sichuan Province,China [2]Key Laboratory of Birth Defects and Related Diseases of Women and Children,Ministry of Education,West China Second University Hospital of Sichuan University,Chengdu 610066,Sichuan Province,China
出 处:《World Journal of Clinical Cases》2022年第20期6974-6980,共7页世界临床病例杂志
基 金:Supported by the Science and Technology Department of Sichuan Province,No. 2020YFS0105;the West China Second University Hospital of Sichuan University,No. KL036
摘 要:BACKGROUND Brain tumors are the most common solid tumors in children and comprise 25%of all malignancies in children.Common presentations include headache,nausea and vomiting,gait abnormality,papilledema,and epileptic seizure;however,some symptoms can be very insidious,with atypical and misleading manifestations.CASE SUMMARY Here,we report a 7-year-old boy who presented with recurrent cyanosis and tachypnea after exercise for 2 years.His body mass index was 26.43 kg/m2.Hepatosplenomegaly,blood gas analysis,biochemical parameters,chest computed tomography scan,and echocardiograph suggested type II respiratory failure,pulmonary heart disease,and mild liver injury.Non-invasive breathing support,antibiotics,and anti-heart failure therapy were given.The patient’s pulse oxygen saturation increased to over 95%when he was awake but dropped to 50%-60%,accompanied by cyanosis,during sleep while receiving high-flow nasal cannula oxygen.Sleep-related breathing disorder was suspected.In the intensive care unit,however,polysomnography was unavailable.Brain magnetic resonance imaging revealed a space-occupying(cerebellum and brainstem)lesion,which was later confirmed to be pleomorphic xanthoastrocytoma by surgery and histopathology by tissue biopsy.CONCLUSION When treating patients with cyanosis and tachypnea,a broad differential diagnosis should be considered,including brain tumor.
关 键 词:Respiratory failure Pulmonary heart disease Sleep-related breathing disorders Pleomorphic xanthoastrocytoma Children Case report
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