Giant retroperitoneal liposarcoma treated with radical conservative surgery: A case report and review of literature  

作　　者：Eva Lieto Francesca Cardella Silvia Erario Giovanni Del Sorbo Alfonso Reginelli Gennaro Galizia Fabrizio Urraro Iacopo Panarese Annamaria Auricchio 

机构地区：[1]Department of Traslational Medical Sciences,University of Campania"L.Vanvitelli",Naples 80128,Campania,Italy [2]Department of Precision Medicine,University of Campania"L.Vanvitelli",Naples 80138,Campania,Italy [3]Depatment of Pathology Unit-Menthal Health,University of Campania"L.Vanvitelli",Naples 80132,Campania,Italy

出　　处：《World Journal of Clinical Cases》2022年第19期6636-6646,共11页世界临床病例杂志

摘　　要：BACKGROUND Retroperitoneal liposarcoma(RLPS)is a rare malignant tumor of the connective tissue and usually grows to a large size,undetected.Diagnosis is currently based on collective findings from clinical examinations and computed tomography(CT)and magnetic resonance imaging,the latter of which show a fat density mass and possible surrounding organ involvement.Surgical resection is the main therapeutic strategy.The efficacy and safety of further therapeutic choices,such as chemotherapy and radiotherapy,are still controversial.CASE SUMMARY A 61-year-old man presented with complaint of a large left inguinal mass that had appeared suddenly,after a slight exertion.Ultrasonography revealed an omental inguinal hernia.During further clinical examination,an enormous palpable abdominal mass,continuing from the left inguinal location,was observed.CT revealed a giant RLPS,with remarkable mass effect and wide visceral dislocation.After multidisciplinary consultation,surgical intervention was performed.Subsequent neoadjuvant chemotherapy and radiotherapy were precluded by the mass’large size and retroperitoneal localization,features typically associated with non-response to these types of treatment.Instead,the patient underwent conservative treatment via radical surgical excision.After 1 year,his clinical condition remained good,with no radiological signs of recurrence.CONCLUSION Conservative treatment via surgery resulted in a successful outcome for a large RLPS.

关 键 词：Retroperitoneal liposarcoma Giant sarcoma Sarcoma surgical treatment Sarcoma diagnosis Differentiated liposarcoma Retroperitoneal sarcoma surgical outcome Case report 

分 类 号：R735.4[医药卫生—肿瘤]