益脑增智针法联合Bobath康复训练治疗手足徐动型脑瘫患儿的临床研究  

Clinical study on Yinao Zengzhi acupuncture combined with Bobath rehabilitation training in the treatment of children with athetotic cerebral palsy

作　　者：丘海美 陆炳林 陈耀星 QIU Haimei;LU Binglin;CHEN Yaoxing(Department of Child Rehabilitation,Traditional Chinese Medicine Hospital of Yulin,Yulin,Guangxi 537000,China)

机构地区：[1]玉林市中医医院儿童康复科,广西玉林537000

出　　处：《现代医学与健康研究电子杂志》2022年第13期30-33,共4页Modern Medicine and Health Research

摘　　要：目的探讨应用益脑增智针法联合Bobath康复训练治疗手足徐动型脑瘫患儿,对其发育情况与免疫功能的影响。方法选取玉林市中医医院2017年1月至2021年1月收治的100例手足徐动型脑瘫患儿,根据随机数字表法将其分为对照组(50例)和观察组(50例)。对照组患儿采取Bobath疗法,观察组患儿在对照组基础上联合使用益脑增智针法治疗,两组均持续治疗6个月。比较两组患儿治疗后临床疗效,治疗前后精细运动功能发育情况、患侧手功能、日常生活能力、智力发育情况、免疫功能及治疗后临床症状发生情况。结果治疗后,观察组患儿临床总有效率高于对照组;与治疗前比,治疗后两组患儿精细运动发育商(FMQ)、Caroll手功能评定量表、日常生活能力量表(ADL)评分及智力发育量表评分均升高,且观察组高于对照组;治疗后两组患儿CD4^(+)CD25^(+)Foxp3^(+)调节性T细胞(Treg细胞)比例、叉状头转录因子P3(Foxp3)mRNA、细胞毒性T淋巴细胞相关蛋白4(CTLA-4)mRNA相对表达量均降低,且观察组低于对照组;治疗后,观察组患儿临床症状总发生率低于对照组(均P<0.05)。结论手足徐动型脑瘫患儿应用益脑增智针法联合Bobath康复训练后,可有效提高智力发育水平与免疫功能,促进精细运动功能、患侧手功能的恢复,改善日常生活能力,同时减少临床症状的发生,提高疗效。Objective To explore the effects of Yinao Zengzhi acupuncture combined with Bobath rehabilitation training on the development and immune function of children with athetotic cerebral palsy.Methods 100 children with athetotic cerebral palsy admitted to Traditional Chinese Medicine Hospital of Yulin from January 2017 to January 2021 were selected and divided into the control group(50 cases)and the observation group(50 cases)according to the random number table method.The children in the control group were treated with Bobath therapy,and the children in the observation group were treated with Yinao Zengzhi acupuncture on the basis of the control group.Both groups were treated for 6 months.The clinical efficacy of the two groups of children after treatment,the development of fine motor function,the hand function of the affected side,the ability of daily living,the development of intelligence,the immune function before and after treatment,and the occurrence of clinical symptoms after treatment were compared between the two groups.Results After treatment,the total clinical effective rate in the observation group was higher than that in the control group;compared with before treatment,the scores of fine motor development quotient(FMQ),Carroll hand function rating scale,activity of daily living scale(ADL)and intelligence development scale in the two groups increased after treatment,and the observation group was higher than the control group;after treatment,the proportion of CD4^(+)CD25^(+)Foxp3^(+)regulatory T cells(Treg cells),the relative expression of forkhead transcription factor P3(Foxp3)mRNA and cytotoxic T lymphocyte associated protein 4(CTLA-4)mRNA in the two groups decreased,and the observation group was lower than the control group;after treatment,the total incidence of clinical symptoms in the observation group was lower than that in the control group(all P<0.05).Conclusion The application of Yinao Zengzhi acupuncture combined with Bobath rehabilitation training in children with athetotic cerebral palsy can eff

关 键 词：手足徐动型脑瘫 益脑增智针法 BOBATH疗法 免疫功能 

分 类 号：R748[医药卫生—神经病学与精神病学]