Imaging characteristics of orbital peripheral nerve sheath tumors:Analysis of 34 cases  

作　　者：Min Dai Ting Wang Jun-Ming Wang Li-Ping Fang Ying Zhao Asmitananda Thakur Dong Wang 

机构地区：[1]Department of Rehabilitation Center for Elderly,Beijing Rehabilitation Hospital Affiliated to Capital Medical University,Beijing 100144,China [2]Department of Respiratory Medicine,Xi'an People's Hospital(The Fourth Xi'an Hospital),Xi'an 710004,Shannxi Province,China [3]Department of Radiology,Xi'an People's Hospital(The Fourth Xi'an Hospital),Xi'an 710004,Shannxi Province,China [4]Department of Pathology,Xi'an People's Hospital(The Fourth Xi'an Hospital),Xi'an 710004,Shannxi Province,China [5]Chest Clinic,NATA,Morang,Biratnagar 0097721,Nepal

出　　处：《World Journal of Clinical Cases》2022年第21期7356-7364,共9页世界临床病例杂志

基　　金：Supported by the Incubation Fund Project of the Xi’an People’s Hospital(The Fourth Xi'an Hospital),No.FZ-75.

摘　　要：BACKGROUND Peripheral nerve sheath tumors(PNSTs),a rare group of neoplasms in the orbit,comprise only 4%of all orbital tumors.At present,there are very few studies detailing the features of these tumors identified using imaging technology.AIM To compare the differences in location,morphology,magnetic resonance imaging(MRI)signal intensity/computed tomography(CT)value,and enhancement degree of tumors of different pathological PNSTs types.METHODS Clinical,pathological,CT,and MRI data were analyzed retrospectively in 34 patients with periorbital sheath tumors diagnosed using histopathology from January 2013 to August 2021.RESULTS Among 34 cases of orbital peripheral nerve sheath tumors,21 were schwannomas,12 were neurofibromas,and 1 was a plexiform neurofibroma.Common clinical symptoms presented by patients with these types of tumors include eyelid swelling,exophthalmos,and limited eye movement.Schwannomas mostly occur in the intramuscular space with small tumor volume and rare bone involvement.Neurofibromas develop in the extrapyramidal space with larger tumor volume and more bone involvement.Radiologically,schwannomas and neurofibromas are characterized by regular morphology and uneven density and signal.One case of plexiform neurofibroma showed tortuous and diffuse growth along the nerve,with a worm-like appearance on imaging.CONCLUSION Different pathological types of orbital peripheral nerve sheath tumors have unique imaging characteristics.Comprehensive consideration of the patient's clinical and imaging manifestations is of great value in the diagnosis of orbital peripheral nerve sheath tumors.

关 键 词：Periorbital nerve sheath tumor SCHWANNOMA NEUROFIBROMA Plexiform neurofibroma Imaging features 

分 类 号：R739.72[医药卫生—肿瘤]