黑果枸杞红色素的食品安全性试验研究  

Food safety test research on the red pigment of Lycium ruthenicum

作　　者：姚思宇[1] 彭亮[1] 张洁宏[1] 黄超培[1] 王彦武[1] 覃辉艳[1] 何励[1] 梁慧莉[1] YAO Si-yu;PENG Liang;ZHANG Jie-hong;HUANG Chao-pei;WANG Yan-wu;QIN Hui-yan;HE Li;LIANG Hui-li(Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention,Nanning,Guangxi 530028,China)

机构地区：[1]广西壮族自治区疾病预防控制中心,广西南宁530028

出　　处：《应用预防医学》2022年第3期206-210,共5页Applied Preventive Medicine

基　　金：广西科技基础条件平台建设项目(12-97-18)。

摘　　要：目的 研究黑果枸杞红色素的食用安全性。方法 采用急性毒性试验、遗传毒性试验和亚慢性毒性试验对其进行安全性评价。结果 黑果枸杞红色素的小鼠急性经口LD_(50)>30 000mg/kg·BW,属无毒级;3项遗传毒性试验结果均为阴性;亚慢性毒性试验中各项检测指标均未见异常。结论 黑果枸杞红色素在本试验条件下为无毒物,未显示有急性、亚慢性毒性及遗传毒性。Objective To study the edible safety of the red pigment of Lycium ruthenicum.Methods Acute toxicity test,genotoxicity test,and sub-chronic toxicity test were used to evaluate its safety.Results The acute oral LD_(50)of the mice with red pigment of Lycium ruthenicum was greater than 30 000 mg/kg·BW,which belonged to non-toxic level.The results of the three genetic genotoxicity test were all negative,and no abnormality was found in the sub-chronic toxicity tests.Conclusion The red pigment of Lycium ruthenicum is non-toxic under the test conditions,and it does not show any acute,sub-chronic toxicity,or genotoxicity.

关 键 词：黑果枸杞红色素 安全性 毒理试验 90天 

分 类 号：R155.5[医药卫生—营养与食品卫生学]