甲状腺相关性眼病危险因素的研究进展  

Research Progress in Risk Factors for Thyroid-Associated Ophthalmopathy

作　　者：喻欣怡 章余兰[1] 吴叶萌 YU Xin-yi;ZHANG Yu-lan;WU Ye-meng(Department of Ophthalmology,the Second Affiliated Hospital of Nanchang University,Nanchang 330006,China)

机构地区：[1]南昌大学第二附属医院眼科,南昌330006

出　　处：《实用临床医学（江西）》2022年第3期113-117,共5页Practical Clinical Medicine

摘　　要：甲状腺相关性眼病(TAO)是一种器官特异性自身免疫性疾病,其发病机制仍不甚清楚。多种危险因素共同参与且协同作用于TAO发生发展,如遗传因素、吸烟、放射性碘治疗史等;低硒以及高血脂含量也与TAO发病相关,而肠道微生物菌群与TAO的致病存在密切联系。了解TAO的相关危险因素,适当预防、密切关注病情进展并给予及时干预,有助于减少该病的发生以及延缓疾病的进展。Thyroid-associated ophthalmopathy(TAO)is an organ-specific autoimmune disease,and its pathogenesis is still unclear.Multiple risk factors,such as genetic factors,smoking,and radioactive iodine treatment history,are involved in the development of TAO.Low selenium and high blood lipid content are also associated with the pathogenesis of TAO.Furthermore,intestinal microflora is closely related to TAO.Understanding of relevant risk factors,proper prevention,close attention to the progress,and timely intervention halps to reduce the occurrence of TAO and delay the progress of the disease.

关 键 词：甲状腺相关性眼病 危险因素 遗传因素 吸烟 放射性碘治疗史 低硒 高血脂 肠道微生物菌 

分 类 号：R771.3[医药卫生—眼科] R581[医药卫生—临床医学]