Structural diversity and biological activity of natural p-terphenyls  

作　　者：Guoliang Zhou Tianjiao Zhu Qian Che Guojian Zhang Dehai Li 

机构地区：[1]Key Laboratory of Marine Drugs,School of Medicine and Pharmacy,Chinese Ministry of Education,Ocean University of China,Qingdao,266003,China [2]Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology,Qingdao,266237,China

出　　处：《Marine Life Science & Technology》2022年第1期62-73,共12页海洋生命科学与技术（英文）

基　　金：supported by the NSFC-Shandong Joint Fund(U1906212,U1606403);the Pilot National Laboratory for Marine Science and Technology(2018SDKJ0401-2,2016ASKJ08-02);the National Natural Science Foundation of China Major Project for Discovery of New Leading Compounds(81991522);the National Science and Technology Major Project for Significant New Drugs Development(2018ZX09735004);the Major National Science and Technology Projects of the Ministry of Science and Technology(81991522);the Fundamental Research Funds for the Central Universities(201941001);Project funded by China Postdoctoral Science Foundation(2017M622286);the Taishan Scholar Youth Expert Program in Shandong Province(tsqn201812021).

摘　　要：p-Terphenyls are aromatic compounds consisting of a central benzene ring substituted with two phenyl groups,and they are mainly isolated from terrestrial and marine organisms.The central ring of p-Terphenyls is usually modified into more oxidized forms,e.g.,para quinone and phenols.In some cases,additional ring systems were observed on the terphenyl-type core structure or between two benzene moieties.p-Terphenyls have been reported to have cytotoxic,antimicrobial,antioxidant andα-glucosidase inhibitory effects.In this review,we will mainly summarize the structural diversity and biological activity of naturally occurring p-Terphenyls referring to the research works published before.

关 键 词：P-TERPHENYL Marine organism STRUCTURE Biological activity CYTOTOXIC 

分 类 号：O62[理学—有机化学]