孕妇环境毒物代谢能力对母婴健康影响的研究及营养干预  

Study on the effect of environmental toxicant metabolism ability of pregnant women on maternal and child health and nutritional intervention

作　　者：孙宇红 张立艳 SUN Yuhong;ZHANG Liyan(Department of Maternal Health,Jingdezhen Maternal and Child Health Hospital in Jiangxi Province,Jingdezhen 333000,China)

机构地区：[1]江西省景德镇市妇幼保健院孕产保健科,江西景德镇333000

出　　处：《中国现代医生》2022年第16期70-73,共4页China Modern Doctor

基　　金：江西省景德镇市科技计划项目(20192SFZC024)。

摘　　要：目的 探讨孕妇环境毒物代谢能力对母婴健康影响及营养干预。方法 回顾性选取2019年7月~2020年7月在江西省景德镇市妇幼保健院孕产保健科产检的孕产妇200例,在确定宫内怀孕、胚胎存活的情况下进行毒物代谢能力的检测,筛选出高风险孕产妇60例,依据干预方法分为接受减少环境暴露和靶向营养干预组(试验组,n=30)和未接受减少环境暴露和靶向营养干预组(对照组,n=30),统计分析两组孕妇泌乳情况、营养素摄入情况、营养缺失情况、妊娠结局、新生儿情况。结果 干预后,试验组患者的2 d泌乳率高于对照组,3、4 d泌乳率均低于对照组(Z=2.450,P<0.05)。试验组孕产妇的蛋白质、钙、铁、铜、维生素B1、维生素B2、维生素C、维生素E摄入量占中国居民膳食营养素参考摄入量的百分比均高于对照组(P<0.05)。试验组产后1个月营养缺失率低于对照组(χ^(2)=4.356,P<0.05)。试验组孕产妇围生期并发症发生率为10.00%(3/30),对照组为26.67%(8/30),差异有统计学意义(P<0.05)。试验组新生儿围生期并发症发生率为10.00%(3/30),对照组为33.33%(10/30),差异有统计学意义(P<0.05)。结论 孕妇环境毒物代谢能力对母婴健康影响大,减少环境暴露和靶向营养干预能够有效改善孕妇的妊娠结局。Objective To study the effect of environmental toxicant metabolism ability of pregnant women on maternal and child health and nutritional intervention. Methods A total of 200 pregnant women who received prenatal examination in the Department of Maternal Health of Jingdezhen Maternal and Child Health Hospital in Jiangxi Province from July 2019 to July 2020 were retrospectively selected to detect the metabolic ability of poisons under the condition of intrauterine pregnancy and embryo survival. Sixty high-risk women were selected and divided into two groups according to the intervention method: the group receiving reduced environmental exposure and targeted nutrition intervention(the experimental group,n=30) and the group not receiving reduced environmental exposure and targeted nutrition intervention(the control group, n=30).The two groups′ lactation,nutrient intake,nutritional deficiency, pregnancy outcomes, and neonatal conditions were statistically analyzed. Results After the intervention, the two-day lactation rate, three-day lactation rate,and four-day lactation rate in the experimental group were higher than those in the control group(Z=2.450,P<0.05). The percentages of protein, calcium,iron, copper, vitamin B1, vitamin B2, vitamin C, and vitamin E intake to the reference intake of dietary nutrients in Chinese residents in the experimental group were higher than those in the control group(P<0.05). The nutritional deficit rate at one month after delivery in the experimental group was lower than in the control group(χ^(2)=4.356,P<0.05).The incidence rate of perinatal complications of experimental group was 10.00%(3/30), the control group was 26.67%(8/30),the difference was statistically significant(P<0.05). The incidence rate of neonatal-perinatal complications of the experimental group was 10.00%(3/30),the control group was 33.33%(10/30), The difference was statistically significant(P<0.05). Conclusion The environmental toxicant metabolic ability in pregnant women has a significant impact on maternal and c

关 键 词：孕妇 环境毒物代谢能力 母婴健康 营养干预 营养素摄入 妊娠结局 新生儿状况 

分 类 号：R714.4[医药卫生—妇产科学]