单孔胸腔镜下肺癌根治术手术疗效及安全性评价  

Evaluation on the efficacy and safety of radical resection of lung cancer under single-port thoracoscopic surgery

作　　者：成强 杨如松 刘政呈 曹彬[1] CHENG Qiang;YANG Ru-song;LIU Zheng-cheng(Nanjing Drum Tower Hospital,The Affiliated Hospital of Nanjing University Medical School,Nanjing 210008,Jiangsu)

机构地区：[1]南京大学医学院附属鼓楼医院心胸外科,江苏南京210008

出　　处：《安徽医专学报》2022年第3期19-21,共3页Journal of Anhui Medical College

基　　金：南京市医学科技计划重点项目(编号:ZKX21015);江苏省科技厅基础研究计划项目(编号:BK20200156)。

摘　　要：目的:比较单孔电视胸腔镜辅助(VATS)肺癌根治术与单操作孔VATS肺癌根治术在早期非小细胞肺癌治疗的术后疗效及安全性。方法:该研究为病例对照研究,选取在2018年1月-2021年7月于南京大学医学院附属鼓楼医院胸外科接受根治性肺叶切除术的NSCLC患者180例。随机分组,其中行单操作孔手术者为对照组,行单孔手术者为观察组。最终对照组90例患者,观察组90例患者。比较两组患者术中出血量、术后引流量、淋巴结检出数目、手术时间、拔除胸管时间、术后住院时间、肺功能指标、术后疼痛评分及术后并发症情况。结果:观察组患者术中出血量、术后引流量、淋巴结检出数目、手术时间和对照组比较,差异无统计学意义(P>0.05);和对照组比较,观察组患者术后肺功能指标高、术后疼痛评分低、拔除胸管和出院时间早,差异具有统计学意义(P<0.05)。观察组患者术后并发症中肺部感染发生例数低于对照组,差异具有统计学意义(P<0.05)。结论:通过医院单中心回顾研究,与单操作孔技术相比,单孔胸腔镜肺癌根治患者术后肺部感染的发生更少,肺功能恢复快、术后疼痛轻、出院时间早,是临床值得推荐的手术方式。Objective:To compare the postoperative efficacy and safety between single hole video-assisted thoracoscopic surgery(VATS)and single hole VATS in the treatment of early non-small cell lung cancer.Methods:This study is a case-control study.180 NSCLC patients underwent radical lobectomy in the thoracic surgery department of Nanjing Drum Tower Hospital,the Affiliated Hospital of Nanjing University Medical School,from January 2018 to July 2021 were selected and randomly divided into the control group with 90 patients underwent single operation hole surgery and the observation group with 90 received single-port surgery.The amount of intraoperative bleeding,postoperative drainage,the number of lymph nodes detected,the operation time,the time of chest extubation,the postoperative hospital stay,pulmonary function indexes,postoperative pain score and postoperative complications were compared between the two groups.Result:There was no significant difference in intraoperative bleeding,postoperative drainage,number of lymph nodes and operation time between the observation group and the control group(P>0.05);Compared with the control group,the observation group had higher postoperative pulmonary function index,lower postoperative pain score,chest tube extraction and early discharge time(P<0.05).There was significant difference in the number of cases of pulmonary infection and atelectasis in the observation group(P<0.05).Conclusion:Through the single center retrospective study in Nanjing Drum Tower Hospital,compared with the single operation hole technology,the patients with single hole thoracoscopic radical resection of lung cancer have less postoperative pulmonary infection and atelectasis,rapid recovery of pulmonary function,less postoperative pain and early discharge time.It is a clinically recommended operation method.

关 键 词：单孔电视胸腔镜手术 非小细胞肺癌 肺癌根治术 

分 类 号：R734.2[医药卫生—肿瘤]