长春西汀与胞二磷胆碱治疗脑梗死对于脑功能恢复的对比  

Comparison of Vinpocetine and Citicoline Treatment of Cerebral Infarction for Recovery of Brain Function

作　　者：鲁翔 LU Xiang(Panjin City People's Hospital,Panjin 124000,China)

机构地区：[1]辽宁省盘锦市人民医院,辽宁盘锦124000

出　　处：《中国医药指南》2022年第18期103-106,共4页Guide of China Medicine

摘　　要：目的分析和对比长春西汀与胞二磷胆碱治疗脑梗死的临床效果及对于脑功能恢复的影响,以期为脑梗死患者找到一种安全、高效的治疗方案。方法本文研究对象选择我院84例脑梗死患者作为,患者收治时间范围为2019年1月至2019年12月,采用单双号法将其分为两组,单号为对照组,双号为研究组,每组42例。对照组采用胞二磷胆碱治疗,研究组采用长春西汀治疗,对比两组患者治疗前后的神经功能缺损评分、生活自理能力评分、语言功能、肢体功能恢复时间、住院时间、治疗总有效率及治疗期间的不良反应发生率。结果治疗前,研究组患者神经功能缺损评分(37.34±2.55)分、生活自理能力评分(49.27±2.08)分与对照组(37.26±2.58)分、(49.22±2.15)分对比无显著差异(P>0.05),治疗后,研究组患者神经功能缺损评分(20.76±1.57)分显著低于对照组(32.18±2.12)分,研究组患者生活自理能力评分(86.84±3.72)分显著高于对照组(65.17±2.26)分,研究组患者语言功能恢复时间(7.34±1.97)d、肢体功能恢复时间(8.62±1.65)d、住院时间(10.33±2.04)d均显著短于对照组(11.68±2.04)d、(13.97±2.15)d、(15.78±2.15)d,研究组患者治疗总有效率(80.95%)显著高于对照组(54.76%),研究组患者治疗期间的不良反应发生率(4.76%)显著低于对照组(19.05%),两组对比具有统计学意义(P<0.05)。结论长春西汀与胞二磷胆碱治疗脑梗死均有一定的效果,但长春西汀对促进患者脑功能恢复的效果更佳,且不良反应发生率更低,因此,其是一种安全、高效的治疗方案,值得临床优先使用和推广。Objective To analyze and compare the clinical effects of vinpocetine and citicoline in the treatment of cerebral infarction and the effect on the recovery of brain function,in order to find a safe and efficient treatment plan for patients with cerebral infarction.Methods The study subjects in this article selected 84 patients with cerebral infarction in our hospital.The patients were admitted for treatment from January 2019 to December 2019.They were divided into two groups by the odd and even number method.The single number was the control group and the double number was study group,42 cases in each group.The control group was treated with citicoline,and the study group was treated with vinpocetine.The neurological deficit score,selfcare ability score,language function,recovery time of limb function,hospitalization time,total effective rate of treatment and incidence of adverse reactions during treatment were compared between the two groups.Results Before treatment,there was no significant difference between the neurological deficit score(37.34±2.55)and the self-care ability score(49.27±2.08)of the study group and the control group(37.26±2.58)and(49.22±2.15)(P>0.05).After treatment,the neurological deficit score(20.76±1.57)of the study group was significantly lower than that of the control group(32.18±2.12),and the score of self-care ability(86.84±3.72)of the study group was significantly higher than that of the control group(65.17±2.26)points.The language function recovery time of the study group was(7.34±1.97)d,the limb function recovery time(8.62±1.65)d,and the hospital stay(10.33±2.04)d were significantly shorter than those in the control group(11.68±2.04)d,(13.97±2.15)d,(15.78±2.15)d,the total effective rate of treatment in the study group(80.95%)was significantly higher than that of the control group(54.76%),the incidence of adverse reactions during the treatment of the study group(4.76%)was significantly lower than the control group(19.05%),and the comparison between the two groups was stati

关 键 词：长春西汀 胞二磷胆碱 脑梗死 脑功能 

分 类 号：R743.33[医药卫生—神经病学与精神病学]