恶性肿瘤患者化疗相关认知障碍与照顾者负担的相关性研究  

Study on the relationship between chemotherapy-related cognitive impairment and caregiver burden in patients with malignant tumor

作　　者：李皓吾 王晓慧[2] 轩菡[1,2] LI Haowu;WANG Xiaohui;XUAN Han(Oncology Teaching and Research Office,The Second Hospital of Anhui Medical University;Department of Oncology,The Second Hospital of Anhui Medical University,Hefei,Anhui 230601,China)

机构地区：[1]安徽医科大学第二附属医院肿瘤学教研室 [2]安徽医科大学第二附属医院肿瘤科,安徽合肥230601

出　　处：《大医生》2022年第13期4-7,共4页Doctor

摘　　要：目的分析恶性肿瘤患者的化疗相关认知障碍与家庭照顾者负担的关系,为临床干预提供参考。方法选取2021年11月至2022年2月安徽医科大学第二附属医院120例恶性肿瘤化疗患者及120例照顾者为研究对象进行回顾性分析,采用一般资料情况调查表、认知功能量表(FACT-Cog)、简明精神状态量表(MMSE)、肿瘤患者家庭照顾者负担量表(CBS-CP)进行调查并予以统计分析。结果本研究共发放问卷120份,回收有效问卷114份;恶性肿瘤患者的FACT-Cog平均总分为(28.18±14.89)分,其中认知正常28例(24.56%),轻度认知障碍68例(59.65%),中度认知障碍18例(15.79%);肿瘤患者家庭照顾者CBS-CP总分平均为(26.96±16.16)分,随感知认知障碍程度加重,照顾者的负担水平不断增加,其中中度组患者的照顾者负担各维度得分及总分均最高(P<0.05);肿瘤患者家庭照顾者负担总分与患者认知程度呈正相关(r=0.598,P<0.05)。结论癌症患者化疗后普遍存在轻度认知功能障碍;肿瘤患者家庭照顾者的照顾负担处于轻度水平,其中家属的心理负担维度最重;肿瘤患者家庭照顾者负担总分与患者认知程度呈正相关。Objective To analyze the relationship between chemotherapy-related cognitive impairment in patients with malignant tumor and the burden of family caregivers,and to provide reference for clinical intervention.Methods From November 2021 to February 2022,120 malignant tumor chemotherapy patients and caregivers from The Second Hospital of Anhui Medical University were investigated and statistically analyzed by general information questionnaire,cognitive function scale(FACT-Cog),mini-mental state examination(MMSE)and the caregiver burden scale for cancer patients(CBS-CP).Results A total of 120 questionnaires were distributed in this study,114 valid questionnaires were recovered.The total FACT-Cog score of malignant tumor patients was(28.18±14.89),of which 28(24.56%)had normal cognition,68(59.65%)had mild cognitive impairment and 18(15.79%)had moderate impairment.The total score of the CBS-CP was(26.96±16.16).With the aggravation of perceived cognitive impairment,the level of caregiver burden increased.The scores of all dimensions and total scores of caregiver burden in the moderate group were the highest(P<0.05).The total score of family caregivers burden of cancer patients were positively correlated with the patient’s cognition(r=0.598,P<0.05).Conclusion Cognitive impairment is common in cancer patients after chemotherapy,mainly mild impairment.The care burden of family caregivers of cancer patients are at a mild level,and the dimension of psychological burden of family members are the heaviest.The total score of family caregivers burden of cancer patients are positively correlated with the patient’s cognition level.

关 键 词：恶性肿瘤 化疗相关认知障碍 家庭照顾者 照顾负担 

分 类 号：R73[医药卫生—肿瘤]