经颅直流电刺激配合镜像神经元疗法治疗缺血性脑卒中后运动性失语症效果观察  

Observation on the effect of transcranial direct current stimulation combined with mirror neuron therapy on motor aphasia after ischemic stroke

作　　者：徐唱 孙文琳[1] 张亚洁 XU Chang;SUN Wen-lin;ZHANG Ya-jie(Department of Rehabilitation, the First People′s Hospital of Huai′an City, Jiangsu Province, Huai′an 223000, China)

机构地区：[1]江苏省淮安市第一人民医院康复科,江苏淮安223000

出　　处：《河北医科大学学报》2022年第7期750-753,774,共5页Journal of Hebei Medical University

摘　　要：目的探讨经颅直流电刺激配合镜像神经元疗法治疗缺血性脑卒中后运动性失语症的效果。方法选取80例缺血性脑卒中后运动性失语症患者,依照随机数字表法分为对照组和试验组,每组40例。两组均给予基础治疗,对照组另给予镜像神经元疗法治疗,试验组在对照组的基础上另给予经颅直流电刺激治疗,两组均治疗20 d。治疗前后采用波士顿诊断性失语症检查(Boston Diagnostic Aphasia Examination,BDAE)、语言功能评分(Western Aphasia Battery,WAB)和神经功能缺损评分(National Institutes of Health Stroke Scale,NIHSS)对两组进行评定,比较两组患者临床疗效及不良反应发生率。结果治疗后2组BDAE等级分布比较差异有统计学意义(P<0.05);治疗后,试验组的总有效率高于对照组(P<0.05);两组治疗后WAB评分均升高(P<0.05),且试验组更高(P<0.05),两组NIHSS评分均降低(P<0.05),且试验组更低(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论经颅直流电刺激配合镜像神经元疗法可提高缺血性脑卒中后运动性失语症患者的语言功能,疗效确切,且安全可靠。Objective To explore the effect of transcranial direct current stimulation combined with mirror neuron therapy on motor aphasia after ischemic stroke.Methods Eighty patients with motor aphasia after ischemic stroke admitted to the hospital were selected and divided into control group(n=40)and experimental group(n=40)according to random number table.Both groups were given basic treatment,the control group was given mirror neuron therapy,and the experimental group was treated with transcranial direct current stimulation on the basis of the control group.Both groups were treated for 20 d.Before and after treatment,the two groups were assessed using the Boston Diagnostic Aphasia Examination(BDAE),Western Aphasia Battery(WAB)and the National Institutes of Health Stroke Scale(NIHSS),and the clinical efficacy,and incidence of adverse reactions were compared between two groups.Results After treatment,the difference in BDAE grade distribution between two groups was statistically significant(P<0.05).After treatment,there was significant difference in the distribution of curative effects between two groups(P<0.05),and the total effective rate of the experimental group was higher than that of the control group(P<0.05).After treatment,the WAB scores of both groups were increased(P<0.05),which were higher in experimental group(P<0.05),and the NIHSS scores of two groups were decreased(P<0.05),and which were lower in experimental group(P<0.05).There was no significant difference in the incidence of adverse reactions between two groups(P>0.05).Conclusion Transcranial direct current stimulation combined with mirror neuron therapy can improve the language function of patients with motor aphasia after ischemic stroke,with a definite effect,good safe and reliability.

关 键 词：卒中 失语 BROCA 电刺激 

分 类 号：R743[医药卫生—神经病学与精神病学]