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作 者:王志宏[1] 张浩[1] WANG Zhi-hong;ZHANG Hao(Department of Thyroid Surgery,the First Hospital of China Medical University,Shenyang 110001,China)
机构地区:[1]中国医科大学附属第一医院甲状腺外科,辽宁沈阳110001
出 处:《中国实用外科杂志》2022年第6期648-652,共5页Chinese Journal of Practical Surgery
基 金:辽宁省自然科学基金(No.2020-MS-143);沈阳市科技计划项目(No.21-173-9-31)。
摘 要:儿童及青少年分化型甲状腺癌少见,与成人相比常具有更高的淋巴结转移发生率、更多的腺外侵犯率以及更高的远处转移发生率和复发率,但总体病死率低于成人。现有儿童及青少年分化型甲状腺癌的指南及共识对于外科治疗的方式提出了推荐意见,但对于这部分病人的个体化治疗仍存在争议。临床应综合考虑这一部分病人的特点,将更加精准的术前评估与个体化外科治疗相结合,在制定外科治疗策略时兼顾肿瘤的彻底根治与功能保护,以期减少并发症,提高生活质量。Differentiated thyroid carcinoma(DTC)in children and adolescents is rare. Compared with adults,children and adolescents DTC often presents higher rate of lymph node metastasis,extrathyroid extension,distant metastasis and recurrence,yet lower overall mortality. There are still controversy on the individualized treatment of these patients in the existing guidelines and consensus recommendations on DTC in children and adolescents. In clinical practice,the characteristics of this part of patients should be comprehensively considered, more accurate preoperative evaluation should be combined with individualized surgical treatment,and surgical treatment strategies should be taken into consideration to radically cure tumors and protect their functions,in order to reduce complications and improve quality of life.
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