肝细胞癌患者缩短普美显强化MRI检查中肝胆期时间的探索  

Exploration of shortening the duration of hepatobiliary phase in EOB enhanced MRI for patients with hepatocellular carcinoma

作　　者：温鹏 韩玉娟[2] 杨剑[2] 纪盛章[1] WEN Peng;HAN Yu-juan;YANG Jian;JI Sheng-zhang(Radiology Center,Fourth Clinical,Tianjin Medical University,Tianjin 300142,China;Department of Radiology,Tianjin Third Central Hospital,Tianjin 300170,China)

机构地区：[1]天津医科大学第四中心临床学院影像科,天津300142 [2]天津市第三中心医院放射科,天津300170

出　　处：《天津医科大学学报》2022年第4期433-435,441,共4页Journal of Tianjin Medical University

基　　金：天津市卫计委重点攻关项目(14KG113)。

摘　　要：目的:探究肝细胞癌(HCC)患者应用15 min肝胆期普美显的临床诊断效果。方法:选择本院收治的80例HCC患者,同一患者分别进行15 min和20 min普美显肝胆期延迟扫描(分为15 min组和20 min组)。比较两组视觉模拟评分(VAS)、患者配合度评分、病灶检出率评分以及图像指标评分。结果:15 min组VAS明显低于20 min组(t=3.14,P=0.003),并且配合度得分更高(t=2.36,P=0.02);两组均表现出有效的病灶检出率(P=0.18);3个动态时期(动脉期、门静脉期和延迟期)均反映出良好的HCC血供情况(均P>0.05);两组对象图像指标评分(Cm和CER)结果对于HCC不同分化程度(高分化、中分化以及低分化)均未表现出显著性差异(均P>0.05)。结论:使用15 min普美显肝胆期时间检测与目前临床使用的20 min在影像结果上无显著差异,但是HCC患者的配合度更高,体验更佳。Objective:To investigate the clinical diagnostic effects of 15 min Gd-EOB-GTPA(EOB)in patients with hepatocellular carcinoma(HCC).Methods:A total of 80 patients with HCC were randomly divided into two groups:15 min and 20 min EOB delayed hepatobiliary phase scan group(15 min group and 20 min group respectively).Visual analogue scale(VAS),patient compliance score,lesion detection rate score and image index score were observed independently.Results:The VAS values of the 15 min group was significantly lower than theVAS values of the 20 min group(t=3.14,P=0.003),and the score of compliance was higher(t=2.36,P=0.02),both groups showed an effective lesion detection rate(P=0.18),three dynamic phases(arterial phase,portal phase and delayed phase)showed good blood supply of HCC(all P>0.05).There was no significant difference between the two groups in the degree of differentiation of HCC(high differentiation,moderate differentiation and low differentiation,all P>0.05).Conclusion:There is no significant difference between 15 min PME and 20 min EOB in imaging diagnosis of HCC,but the patients with HCC have better cooperation and experience,which is worthy of clinical application in future.

关 键 词：普美显 肝细胞肝癌 MRI 肝胆期时间 

分 类 号：R735.7[医药卫生—肿瘤]