切口选择对女性浸润性乳腺癌前哨淋巴结检出及皮下积液的影响  

Effect of incision selection on sentinel lymph node detection and subcutaneous effusion in female invasive breast cancer

作　　者：杨丽 何建信 张春霞 马强 YANG Li;HE Jianxin;ZHANG Chunxia;MA Qiang(General Surgery,Beijing Shunyi Hospital,Beijing 101300,China;General Surgery,Horqin Left Middle Banner Peoples Hospital,Tongliao,Inner Mongolia Autonomous Region 029399,China)

机构地区：[1]北京市顺义区医院普外二科,北京101300 [2]通辽市科尔沁左翼中旗人民医院外二科,内蒙古自治区通辽029399

出　　处：《安徽医药》2022年第8期1623-1626,共4页Anhui Medical and Pharmaceutical Journal

摘　　要：目的探讨女性浸润性乳腺癌(IBC)病人前哨淋巴结活检(SLNB)手术切口选择对前哨淋巴结(SLN)的检出、术后腋下引流时间及皮下积液发生情况的影响。方法回顾性分析2015年9月至2019年12月北京市顺义区医院行SLNB的女性IBC病人297例临床病理资料,根据SLNB切口不同分为乳腺切口组149例及腋下切口组148例,比较两组SLN检出率、检出数目、术后腋下引流时间及皮下积液发生情况。结果SLN的检出率为97.31%,乳腺切口组为96.64%,平均检出SLN(3.58±1.53)枚,腋下切口组SLN检出率为97.97%,平均检出SLN(3.27±1.52)枚,两组SLN检出率及数目差异无统计学意义(P>0.05);SLN阴性病人,腋下切口组的引流时间长于乳腺切口组[(6.25±1.62)d比(5.46±1.34)d,P<0.05],SLN阳性者两组引流时间差异无统计学意义(P>0.05);两组皮下积液发生率差异无统计学意义(P>0.05)。结论两种切口进行SLNB对SLN的检出率及检出数目相当,虽然SLN阳性者两种切口引流时间及并发症发生相当,但对于SLN阴性者,乳腺切口引流时间更短,积液发生率更低,乳腺切口进行SLNB值得临床进一步推广使用。Objective To investigate the effect of incision selection of sentinel lymph node biopsy on sentinel lymph node(SLN)detection,axillary drainage time and subcutaneous effusion in female patients with invasive breast cancer(IBC).Methods The clinicopathological data of 297 female patients with IBC who underwent SLNB in Beijing Shunyi Hospital from September 2015 to December 2019 was retrospectively analyzed.They were divided into breast incision group and axillary incision group according to different incision for SLNB.The detection rate and number of SLN,the time of axillary drainage and the occurrence of subcutaneous hydrops in two different incision groups were compared.Results The detection rate of SLN was 97.31%.96.64% in breast incision group and 97.97% in axillary incision group.The average number of SLN was(3.58±1.53)in breast incision group and(3.27±1.52)in axillary incision group.There was no significant difference in detection rate and number of SLN between the two groups(P>0.05).For the patients with negative SLN,the time of axillary drainage in axillary incision group was longer than that in breast incision group[Mean drainage time(6.25±1.62)d vs.(5.46±1.34)d,P<0.05].For patient with positive SLN,there was no significant difference in drainage time between the two groups(P>0.05).The incidence of subcutaneous effusion in breast incision group was lower than that in axillary incision group,but the difference was not significant(P>0.05).Conclusions The detection rate and number of SLN in the two incisions are the same.For the patients with positive SLN,the drainage time and complications between the two incisions groups are similar.For the patients with negative SLN,the drainage time is shorter and the incidence of effusion is lower by breast incision.SLNB through breast incision is worthy of further clinical application.

关 键 词：乳腺肿瘤 前哨淋巴结活检 切口 引流 皮下积液 

分 类 号：R737.9[医药卫生—肿瘤]