A puzzling case of differentiation syndrome mimicking SARS-CoV2 pneumonitis: a case report  

作　　者：B.Namratha Sai Reddy Nishith Vaddeboina Ch.Shyny Reddy 

机构地区：[1]Department of Medical Oncology,Omega Hospitals,Hyderabad,Telangana 500034,India

出　　处：《Cancer Advances》2022年第13期1-3,共3页TMR肿瘤进展

摘　　要：Differentiation syndrome is a complication commonly encountered in acute promyelocytic leukemia patients when treated with Al-Trans retinoic acid.This Differentiation syndrome has veryclose similarities clinically and radiologically to SARS-CoV2 pneumonitis which makes diagnosis of differentiation syndrome challenging specially during this COVID-19 pandemic.We hereby report a case of a 68-year-old male with acute promyelocytic leukemia who on initiation of Al-Trans retinoic acid developed acute respiratory distress with radiological findings of multiple ground glass opacities in bilateral lungs suggestive of SARS-CoV2 pneumonitis.Considering the radiological similarities to differentiation syndrome and on high clinical suspicion,this patient was immediately started on steroids with which he recovered rapidly.During this pandemic of SARS-CoV2,distinguishing differentiation syndrome from SARS-CoV2 pneumonitis clinically and radiologically is extremely challenging.

关 键 词：differentiation syndrome SARS-CoV2 pneumonitis LEUKEMIA 

分 类 号：R73[医药卫生—肿瘤]