不同术式内镜逆行胰胆管造影术对Oddi括约肌功能的影响研究进展  

Research progress in effect of endoscopic retrograde cholangiopancreatography on Oddi sphincter function

作　　者：焦黎 王军民 Jiao Li;Wang Jun-Min(Department of Gastroenterology,the Third Hospital of Hebei Medical University,Shijiazhuang 050000,China)

机构地区：[1]河北医科大学第三医院消化科,石家庄050000

出　　处：《解放军医学杂志》2022年第6期607-613,共7页Medical Journal of Chinese People's Liberation Army

基　　金：河北省重点研发计划项目(19277729D)。

摘　　要：Oddi括约肌是控制胆胰管通道的重要阀门,其损伤会造成肠胆反流,引起反流性胆管炎、胆囊炎、结石再发,以及胆管癌等一系列远期并发症。胆总管结石作为临床最常见的消化系统疾病之一,近年来发病率逐渐增高。内镜逆行胰胆管造影术(ERCP)是治疗胆总管结石的首选微创方法,已广泛应用于临床,但其可能对Oddi括约肌造成损伤。本文对ERCP的几种主要术式(内镜下乳头括约肌切开术、内镜下十二指肠乳头气囊扩张术、内镜下乳头括约肌小切开联合气囊扩张术、内镜下钛夹乳头成形术)对Oddi括约肌功能的影响进行综述。Oddi sphincter is an important valve controlling the biliopancreatic duct passage,and its injury can cause enterobiliary reflux,resulting in a series of long-term complications such as reflux cholangitis,cholecystitis,recurrence of calculi,and even cholangiocarcinoma.As one of the most common diseases of digestive system,choledocholithiasis is increasing year by year in recent years.Endoscopic retrograde cholangiopancreatography(ERCP)is the preferred minimally invasive method for the treatment of choledocholithiasis and has been widely used in clinical practice.But different ERCP procedures may damage Oddi sphincter.This article reviews the effects of ERCPs(endoscopic sphincterotomy,endoscopic papillary balloon dilation,endoscopic sphincterotomy plus balloon dilation,endoscopic endoclip papilloplasty)on Oddi sphincter and their respective advantages and disadvantages and application prospect.

关 键 词：奥狄括约肌 胰胆管造影术 内镜逆行 内镜下乳头括约肌切开术 内镜下十二指肠乳头气囊扩张术 胆总管结石 

分 类 号：R575.7[医药卫生—消化系统]