经直肠前列腺超声造影与实时弹性成像对前列腺良恶性疾病的诊断价值  

Diagnostic value of contrast-enhanced ultrasound and transrectal real-time elastography for benign and malignant prostate diseases

作　　者：杨浩 陶璇 施颉 李乔 朱镕祥 YANG Hao;TAO Xuan;SHI Jie;LI Qiao;ZHU Rongxiang(Department of Ultrasound,Taizhou Hospital of Traditional Chinese Medicine,Jiangsu Province,Taizhou 225300,China)

机构地区：[1]江苏省泰州市中医院超声科,江苏泰州225300

出　　处：《中国当代医药》2022年第20期130-134,共5页China Modern Medicine

基　　金：江苏省泰州市科技支撑计划(社会发展)项目(TS201908)。

摘　　要：目的探讨经直肠前列腺超声造影(CEUS)与实时弹性成像(TRTE)对前列腺良恶性疾病的诊断价值。方法选取2019年6月至2021年12月泰州市中医院收治的行直肠前列腺穿刺活检的135例患者(146个病灶)的临床资料进行回顾性分析,以穿刺活检病理诊断结果为金标准,比较TRTE与CEUS检查对前列腺良恶性病变的诊断价值。结果良性病灶TRTE检查时的弹性应变率比值(SR)低于恶性病灶,差异有统计学意义(P<0.05)。CEUS联合TRTE诊断良恶性前列腺病灶的准确性为93.84%(137/146),特异性为96.92%(63/65),敏感度为91.36%(74/81),阳性预测值为90.00%(63/70),阴性预测值为97.37%(74/76),联合诊断的曲线下面积(AUC)高于CEUS及TRTE单独诊断,差异有统计学意义(P<0.05)。结论CEUS与TRTE联合能提高对前列腺良恶性疾病的诊断效能,在前列腺穿刺活检中具有较高的应用价值。Objective To explore the diagnostic value of contrast-enhanced ultrasound(CEUS)and transrectal real-time elastography(TRTE)for the benign and malignant prostate diseases.Methods The clinical data of 135 patients(146 lesions)who underwent rectal prostate biopsy in Taizhou Hospital of Traditional Chinese Medicine from June 2019 to December 2021 were retrospectively analyzed,and the diagnostic value of TRTE and CEUS in benign and malignant prostate lesions was compared with the pathological diagnosis results of biopsy as the gold standard.Results The strain ratio(SR)of benign lesions was lower than that of malignant lesions during TRTE examination,and the difference was statistically significant(P<0.05).The accuracy of CEUS combined with TRTE in diagnosing benign and malignant prostate lesions was 93.84%(137/146),the specificity was 96.92%(63/65),the sensitivity was 91.36%(74/81),the positive predictive value was 90.00%(63/70),and the negative predictive value was 97.37%(74/76).The area under curve(AUC)of combined diagnosis was higher than CEUS and TRTE alone,and the difference was statistically significant(P<0.05).Conclusion The combination of CEUS and TRTE can improve the diagnostic efficiency of benign and malignant prostate diseases,and has a high application value in prostate biopsy.

关 键 词：前列腺 超声造影 实时弹性成像 穿刺 活检 良恶性病变 

分 类 号：R737.25[医药卫生—肿瘤]