乳腺鳞状细胞癌的多模态影像学特征及其与腋窝淋巴结转移相关性  

Multimodal Imaging Features of Squamous Cell Carcinoma of the Breast and Their Relationship with Axillary Lymph Node Metastasis

作　　者：颜美莹 阮磊 杨琛 陈丽羽 徐栋 YAN Mei-ying;RUAN Lei;YANG Chen;CHEN Li-yu;XU Dong(The Cancer Hospital ofthe University of Chinese Academy of Sciences(Zhejiang Cancer Hospital)Insti tute ofBasic Medicine and CancerIBMC Chinese Academy of Sciences,Hangzhou 310022,China)

机构地区：[1]中国科学院大学附属肿瘤医院(浙江省肿瘤医院),中国科学院基础医学与肿瘤研究所,浙江杭州310022

出　　处：《肿瘤学杂志》2022年第5期364-369,共6页Journal of Chinese Oncology

摘　　要：[目的]探究乳腺鳞状细胞癌病灶的超声、磁共振、X线钼靶的影像学特征及其与腋窝淋巴结转移的相关性。[方法]回顾性分析2007年11月至2021年5月期间的术后病理或粗针穿刺诊断乳腺鳞状细胞癌38例患者的超声、磁共振、X线影像学资料、临床资料及术后的病理资料。[结果]乳腺鳞状细胞癌38例,腋窝淋巴结未转移共24例(63.16%)。乳腺鳞状细胞癌病灶的超声表现主要为形状不规则(81.58%,31/38)、边界不清(65.79%,25/38)和低回声为主(60.53%,23/38)。MRI特征主要包括形状不规则(68.18%,15/22)、边界不清(68.18%,15/22)、增强模式以不均质增强为主(81.82%,18/22),TIC曲线以Ⅱ型为主(72.73%,16/22)。肿块型病灶的X线影像学特征主要表现为形状不规则(77.78%,21/27)、边界不清(70.37%,19/27)和高密度(66.67%,18/27)。乳腺X线表现可见钙化者占82.14%(23/28)。相对于腋窝淋巴结转移组,腋窝淋巴结未转移组的磁共振影像表现多为不均质强化(P=0.046),腋窝淋巴结未转移组更容易出现钙化的超声表现(P=0.015)。[结论]乳腺鳞状细胞癌的影像学特征大多表现为边界不清的不规则肿块,腋窝淋巴结转移与特定影像学特征存在一定相关性。[Objective]To explore the imaging features of ultrasonography,magnetic resonance and X-ray of lesions in patients with squamous cell carcinoma(SCC)of the breast and their relationship with axillary lymph node metastasis.[Methods]The imaging,clinical and pathological data of 38 cases with breast squamous cell carcinoma admitted in Zhejiang Cancer Hospital from November 2007 to May2021 were retrospectively analyzed.[Results]Among 38 cases,there were 24 cases with negative axillary lymph node metastasis(63.16%).The ultrasound features of breast lesions were mainly irregular shape(81.58%,31/38),unclear boundary(65.79%,25/38)and hypoechoic mass(60.53%,23/38).Magnetic resonance(MRI)features of breast lesions were mainly irregular shape(68.18%,15/22),unclear boundary(68.18%,15/22),inhomogeneous enhancement mode(81.82%,18/22)and TIC curve typeⅡ(72.73%,16/22).The X-ray imaging features of lesions mainly irregular shape(77.78%,21/27),unclear boundary(70.37%,19/27)and high density(66.67%,18/27).Mammography showed calcification in 23 cases(82.14%).Compared with the axillary lymph node metastasis group,the MRI findings of the negative metastasis group were more heterogeneous enhancement(P=0.046)and more calcification in the mammography(P=0.015).[Conclusion]This study shows that the imaging features of SCC of the breast are mostly irregular masses with unclear boundary,and axillary lymph node metastasis may present some specific imaging features.

关 键 词：乳腺鳞状细胞癌 多模态影像 腋窝淋巴结转移 

分 类 号：R737.9[医药卫生—肿瘤]