脑电图、短潜伏期体感诱发电位和经颅多普勒超声在脑死亡判定中的应用  

Application of Electroencephalogram,Short Latency Somatosensory Evoked Potential and Transcranial Doppler Ultrasound in the Determination of Brain Death

作　　者：刘博虎 谢仁华 董权[2] 岑键昌[1] 常谦[1] LIU Bohu;XIE Renhua;DONG Quan;CEN Jianchang;CHANG Qian(Dept.of Neurosurgery,The 1st Hospital of Kunming,Kunming Yunnan 650100,China;ICU,The 1st Hospital of Kunming,Kunming Yunnan 650100,China)

机构地区：[1]昆明市第一人民医院神经外科,云南昆明650100 [2]昆明市第一人民医院ICU,云南昆明650100

出　　处：《昆明医科大学学报》2022年第8期132-137,共6页Journal of Kunming Medical University

基　　金：昆明市卫生健康委员会卫生科研课题基金资助项目(2020-04-04-113)。

摘　　要：目的探究脑电图、短潜伏期体感诱发电位和经颅多普勒超声在脑死亡判定中的价值和应用。方法收集昆明市第一人民医院经临床判定为脑死亡的患者31例,对每位患者均进行2次脑电图、短潜伏期体感诱发电位和经颅多普勒超声检测,根据脑死亡确认实验标准将其分为脑死亡阳性组和脑死亡阴性组,比较3种检查方式的敏感性、特异性和准确性。结果脑电图的敏感性、特异性和准确性均高于短潜伏期体感诱发电位和经颅多普勒超声检测,其敏感性为100%、特异性为75%和准确性为93.55%。脑死亡组脑电图和短潜伏期体感诱发电位阳性人数显著高于非脑死亡组,差异有统计学意义(P<0.05)。结论ROC曲线分析显示脑电图对诊断脑死亡效果佳。Objective To explore the value and application of electroencephalogram,short latency somatosensory evoked potential and transcranial Doppler ultrasound in the determination of brain death.Methods 31 patients with brain death in our hospital were enrolled.Each patient was tested twice by electroencephalogram,short latency somatosensory evoked potential and transcranial Doppler ultrasound.According to the experimental standard of brain death confirmation,they were divided into brain death positive group and brain death negative group.The sensitivity,specificity and accuracy of the three tests were compared.Results The sensitivity,specificity and accuracy of EEG were higher than those of short latency somatosensory evoked potentials and transcranial Doppler,with sensitivity of 100%,specificity of 75%and accuracy of 93.55%.The number of positive EEG and short latency somatosensory evoked potential in brain death group was significantly higher than that in non-brain death group,the difference was statistically significant(P<0.05).Conclusion ROC curve analysis showed that electroencephalogram was effective in diagnosing brain death.

关 键 词：脑死亡 脑电图 短潜伏期体感诱发电位 经颅多普勒超声 

分 类 号：R74[医药卫生—神经病学与精神病学] R459.7[医药卫生—临床医学]