创新化学实验:水杨酸异戊酯的制备  

Innovative Chemical Experiment:Preparation of Isoamyl Salicylate

作　　者：黎古丹 杨金辉[1] 莫琰 卢璐 谭大志[1] LI Gu-Dan;YANG Jin-Hui;MO Yan;LU Lu;TAN Da-Zhi(Experiment Center of Chemistry,Dalian University of Technology,Dalian 116023,China)

机构地区：[1]大连理工大学基础化学实验中心,辽宁大连116023

出　　处：《化学教育（中英文）》2022年第12期40-42,共3页Chinese Journal of Chemical Education

基　　金：大连理工大学研究生教学改革基金项目(JG_2019020)。

摘　　要：酯化反应是有机化学教学实验中最重要的实验种类,不同的酯合成方法有很大区别,这些实验培养了学生的实践能力,在教学实验的基础上,对水杨酸和异戊醇的酯化反应进行了研究探索。水杨酸异戊酯是一种前景广阔,极具开发价值的产品,研究其合成方法具有很大的潜在经济效益和社会效益。采用分水分馏方法,以环己烯为带水剂,高效合成水杨酸异戊酯,产品收率达85.9%。通过研究水杨酸异戊酯的合成方法,培养了学生独立思考的创新能力和勇于探索的科学精神,达到了良好的教学效果。Esterification reaction is the most important type of experiment in organic chemistry teaching experiment.Different methods of ester synthesis are quite different,which can cultivate students’practical ability.Based on the teaching experiment,this paper investigates the esterification of salicylic acid and isoamyl alcohol.Isoamyl salicylate is a product with broad prospects and great development value.Studying its synthesis method has great potential economic benefits and social benefits.Isoamyl salicylate was synthesized by water fractionation with cyclohexene as water carrying agent.The yield was 85.9%.By studying the synthetic method of isoamyl salicylate,the students’innovative ability of independent thinking and the scientific spirit of exploration were cultivated,and good teaching effect was achieved.

关 键 词：水杨酸异戊酯 酯化反应 环己烯 水杨酸 分馏 

分 类 号：G642.423[文化科学—高等教育学] TQ245.24-4[文化科学—教育学]