3D打印导板在牙列缺损修复中应用效果及对龈沟炎性反应生活质量的影响  

Effectiveness of 3D Printed Guides in the Restoration of Dentition Defects and the Effect on the Inflammatory Response of the Gingival Sulcus and Quality of Life

作　　者：蔡若林 毕玮[2] 余优成[2] CAI Ruolin;BI Wei;YU Youcheng(Xiamen Hospital of Zhongshan Hospital Affiliated to Fudan University,Fujian Xiamen 361015,China)

机构地区：[1]复旦大学附属中山医院厦门医院,福建厦门361015 [2]复旦大学附属中山医院,上海200032

出　　处：《河北医学》2022年第7期1182-1188,共7页Hebei Medicine

基　　金：国家自然科学基金资助项目,(编号:82170990)。

摘　　要：目的:探讨3D打印导板在牙列缺损修复中应用效果及对龈沟炎性反应、生活质量的影响。方法:选取2019年10月至2020年10月复旦大学附属中山医院厦门医院86例牙列缺损患者(86颗牙齿),随机数字表法分组,各43例(各43颗牙齿)。对照组采用传统种植导板,研究组采用3D打印导板。统计两组种植体存活率、种植体尖部及颈部偏离值、并发症,比较手术前后咀嚼效率、咬合力、龈沟液炎性因子[白细胞介素-6(IL-6)、白细胞介素-8(IL-8)、肿瘤坏死因子-α(TNF-α)]、口腔健康影响程度量表(OHIP-14)。结果:研究组尖部、颈部近远中向、颊舌向、垂直向偏离值低于对照组(P<0.05);术后随访12个月,研究组种植体存活率100.00%高于对照组存活率75.00%(P<0.05);术后6个月、12个月两组咀嚼效率、咬合力及IL-6、IL-8、TNF-α水平高于术前(P<0.05);两组并发症发生率比较,差异无统计学意义(P>0.05);术后6个月、12个月两组OHIP-14评分均高于术前(P<0.05)。结论:3D打印导板应用于牙列缺损修复患者,有助于缩小种植体尖部及颈部偏离值,提高种植体存活率,改善生活质量,且对龈沟液炎性反应影响较小。Objective:To investigate the application effect of 3D printed guide in dentition defect restoration and its effect on gingival sulcus inflammatory reaction and quality of life.Methods:A total of 86 patients with dentition defects(86 teeth)from October 2019 to October 2020 in our hospital were selected and grouped by random number table method,43 cases in each(43 teeth in each).The control group had traditional implant guides and the study group had 3D printed guides.The implant survival rate,implant cusp and neck deviation values,and complications of the 2 groups were counted,and the masticatory efficiency,occlusal force,gingival sulcus fluid inflammatory factors[interleukin-6(IL-6),interleukin-8(IL-8),tumor necrosis factor-α(TNF-α)],and oral health impact scale(OHIP-14)were compared before and after the surgery.Results:The deviation values of apex,neck mesio-distal,buccal-lingual,and vertical in the study group were lower than those in the control group(P<0.05);At 12 months postoperative follow-up,the survival rate of the implants in the study group was 100.00% compared to 75.00% in the control group(P<0.05);Masticatory efficiency,occlusal force and IL-6,IL-8 and INF-α levels were higher in both groups at 6 and 12 months postoperative than preoperative(P<0.05).There was no significant difference in the incidence of complications between the two groups(P>0.05);(5)OHIP-14 scores were higher than those before operation(P<0.05).Conclusion:The application of 3D printed guide plate in patients with dentition defect repair helps reduce the deviation of implant tip and neck,improve implant survival rate,improve quality of life,and has less effect on gingival crevicular fluid inflammatory reaction.

关 键 词：牙列缺损 口腔种植修复 3D打印导板 炎性反应 生活质量 

分 类 号：R783.6[医药卫生—口腔医学]