利塞膦酸钠片致过敏性休克1例分析  

One case of anaphylactic shock caused by risedronate sodium tablets

作　　者：杨莲娣 YANG Liandi(Clinical Pharmacy,Hengyang Hospital of Traditional Chinese Medicine,Hengyang Hunan 421001,China)

机构地区：[1]湖南衡阳市中医医院临床药学,湖南衡阳421001

出　　处：《中国药物警戒》2022年第7期795-798,共4页Chinese Journal of Pharmacovigilance

摘　　要：目的 提醒在临床使用利塞膦酸钠片时应注意用药安全。方法 通过分析2020年3月发生的1例由利塞膦酸钠片导致的过敏性休克病例及文献回顾利塞膦酸钠片常见的不良反应和致过敏性休克的发病机制。结果 根据患者的临床表现及药物与用药时间的关联性,考虑利塞膦酸钠片导致过敏性休克可能性大,患者经积极抗过敏治疗及对症支持治疗后,过敏性休克症状得到缓解。结论 对有药物过敏史的患者,临床开具患者初次使用口服药物时应慎重。Objective To alert clinicians to adverse drug reactions induced by risedronate sodium tablets.Methods The clinical data of one case of anaphylactic shock caused by risedronate sodium tablets in March 2020 was analyzed while literature related to the common adverse reactions and pathogenesis of anaphylactic shock caused by risedronate sodium tablets was reviewed.Results Based on the patient’s clinical manifestations and the correlations between the drug and the time of medication,it was suspected that risedronate sodium tablets might have caused anaphylactic shock.The patient’s symptoms were relieved after active anti-allergic treatment and symptomatic treatment.Conclusion For patients with a history of drug allergy,oral drugs prescribed for the first time should be selected with caution.

关 键 词：利塞膦酸钠片 口服制剂 过敏性休克 

分 类 号：R994.11[医药卫生—毒理学]