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作 者:Siyu Zhao Xuetao Yang Yingying Xu Zhenzhen Weng Lan Liao Xiaolei Wang
机构地区:[1]The Affiliated Stomatological Hospital,Nanchang University,Nanchang 330006,China [2]The National Engineering Research Center for Bioengineering Drugs and the Technologies,Institute of Translational Medicine,Nanchang University,Nanchang 330088,China [3]The Key Laboratory of Oral Biomedicine,Nanchang 330006,China [4]College of Chemistry,Nanchang University,Nanchang 330088,China
出 处:《Nano Research》2022年第6期5245-5255,共11页纳米研究(英文版)
基 金:the National Natural Science Foundation of China(No.31860263 to X.L.W.and and No.81960492 to L.L.);Key Youth Project of Jiangxi Province(No.20202ACB216002 to X.L.W.);Natural Science Foundation of Jiangxi Province(No.S2018ZRZDB0255 to L.L.);Nanchang University Seed Grant for Biomedicine.
摘 要:Effective dental care can reduce the incidence of oral diseases(dental caries,dentin sensitivity,tooth discoloration,etc.).However,delayed or inappropriate usage of care tools not only fails to eliminate external adverse stimuli,but sometimes even causes dental injury.Inspired by the traditional culture of“lacquer teeth”,a sprayable superhydrophobic protectant(ZFP)composed of ZnO,fluorine modified nano-silica(FSNs),and polydimethylsiloxane(PDMS)is constructed similar to automobile wax,for routine dental protection.With its superhydrophobic properties,this protective membrane can effectively resist the adhesion of bacteria,proteins,and food residues to the teeth surface.Meanwhile,ZFP exerts stable superhydrophobic selfcleaning properties under external mechanical stimulation,temperature alternation,and acidic environment.In addition,ZnO in ZFP can significantly restrain the growth of dental caries-related bacteria(Streptococcus mutans),with an enhanced antibacterial capacity when combined with yellow light irradiation.Both in vivo and in vitro experiments demonstrate that ZFP is a safe,convenient,and quadruplex-effective dental protectant,which is expected to serve as a promising toothpaste companion for joint maintenance of dental health.
关 键 词:dental membrane SUPERHYDROPHOBICITY ZnO antibacterial photocatalysis
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