Patient with unresectable colorectal liver metastases and asymptomatic primary tumor:end of the debate!  

作　　者：Marc-Antoine Allard RenéAdam 

机构地区：[1]Centre Hépato-Biliaire,Hôpital Paul Brousse,APHP,Villejuif,France [2]Équipe Chronothérapie,Cancers et Transplantation,UniversitéParis,Saclay,France

出　　处：《Hepatobiliary Surgery and Nutrition》2022年第3期412-414,共3页肝胆外科与营养（英文）

摘　　要：In patients with definitively unresectable colorectal liver metastases,whether the primary tumor should be resected prior to chemotherapy is an old question.Several retrospective studies(1-5)and a meta-analysis with individual data(6)had suggested that primary resection of the primary tumor followed by chemotherapy was associated with better survival than the chemotherapy-first strategy.The prevention of complications related to the primary tumor(occlusion,perforation,bleeding)as well as a better response to chemotherapy were usual justifications to explain the superiority of primary tumor resection-first.However,the absence of any randomized study made it difficult to conclude on this question due to the numerous selection biases related to these retrospective analyses.

关 键 词：CHEMOTHERAPY COLORECTAL prevention 

分 类 号：R73[医药卫生—肿瘤]