儿童慢性腹泻相关的神经内分泌肿瘤  

Neuroendocrine neoplasms associated with chronic diarrhea in children

作　　者：曹梦莹(综述) 许玲芬(审校)[1] Cao Mengying;Xu Lingfen(Pediatric Gastroenterology of Shengjing Hospital Affiliated to China Medical University,Shenyang 110004,China)

机构地区：[1]中国医科大学附属盛京医院小儿消化科,沈阳110004

出　　处：《国际儿科学杂志》2022年第5期334-337,共4页International Journal of Pediatrics

摘　　要：肿瘤相关性腹泻是儿童慢性腹泻的少见病因,多为神经内分泌肿瘤特异性功能综合征的临床表现之一。腹泻可作为其首发症状出现,也可伴随疾病进展而发生,手术切除肿瘤后症状普遍得到缓解或治愈。该文重点介绍几种常见的儿童慢性腹泻相关的神经内分泌肿瘤,叙述其腹泻特点、腹泻机制及诊治要点,以期提高早期诊断率,改善患儿的预后及生存质量。Tumor-related diarrhea is a rare cause of chronic diarrhea in children,which is usually one of the clinical manifestations of specific functional syndrome of neuroendocrine neoplasms.Diarrhea may appear as the initial symptom or accompany symptom of disease progression,and it is generally relieved or cured after surgical resection.The present review mainly introduces several common neuroendocrine neoplasms which cause chronic diarrhea in children,and summarizes their different diarrhea features and mechanisms,as well as key points in diagnosis and treatment,in order to improve the rate of early diagnosis and prognosis of children.

关 键 词：儿童 腹泻 神经内分泌肿瘤 血管活性肠肽瘤 胃泌素瘤 

分 类 号：R73[医药卫生—肿瘤]