Disseminated histoplasmosis in a 17-year-old Nigerian male patient:A case report  

作　　者：Atana Uket Ewa Bassey Ewa Ekeng Glory Ekpo Bassey Enobong Ufot Akpah Osamagbe Aiyudubie Asemota Livinus Nwancho Nweke 

机构地区：[1]Department of Paediatrics,University of Calabar,Calabar,Nigeria [2]Department of Paediatrics,University of Calabar Teaching Hospital,Calabar,Nigeria [3]Medical Mycology Society of Nigeria [4]Department of Medical Microbiology and Parasitology,University of Calabar Teaching Hospital,Calabar,Nigeria

出　　处：《Asian Pacific Journal of Tropical Medicine》2022年第6期283-286,共4页亚太热带医药杂志（英文版）

摘　　要：Rationale:Disseminated histoplasmosis is the most severe form of histoplasmosis and often associated with fatal outcomes.Both pulmonary and disseminated forms mimics tuberculosis(TB)and may be misdiagnosed.Patient concerns:A 17-year-old male patient compliant with anti-tuberculosis therapy with complaints of fever,cough productive of thick yellowish sputum,fast breathing,abdominal pain,swelling and jaundice.HIV status was negative.Diagnosis:Disseminated histoplasmosis.Interventions:Antimicrobials including anti-TB therapy,ceftriaxone,gentamicin,azithromycin and ciprofloxacin.Outcomes:He was responding to anti-TB drugs until about 4 and a half months on treatment when he fell ill.Peripheral blood film done 2 days prior to his demise revealed florid yeast like organisms in monocytes with eccentric chromatin suggestive of Histoplasma capsulatum.Lessons:Histoplasmosis can both mimic and coexist with TB and so a high index of suspicion is needed for its diagnosis.

关 键 词：HISTOPLASMOSIS DISSEMINATED TUBERCULOSIS SEPSIS Case report 

分 类 号：R725.1[医药卫生—儿科]