伢典微创凝胶去龋技术治疗龋齿的疗效探讨  

Efficacy of carisolv chemo-mechanical caries removal technique in the treatment of caries

作　　者：刘世员 LIU Shiyuan(Dezhou Third People's Hospital(People's Hospital of Lingcheng District),Dezhou 253500,China)

机构地区：[1]德州市第三人民医院(德州市陵城区人民医院),253500

出　　处：《中国现代药物应用》2022年第12期6-10,共5页Chinese Journal of Modern Drug Application

摘　　要：目的探究龋齿治疗中伢典微创凝胶去龋技术治疗龋齿的临床疗效。方法132例龋齿患儿,依据随机原则分为观察组和对照组,各66例。对照组采用传统牙钻磨牙技术进行治疗,观察组采用伢典微创凝胶去龋技术进行治疗。比较两组患儿治疗效果、术中疼痛敏感程度、充填效果、充填面积占比、充填时间、治疗时间、家长满意度及治疗前后疼痛程度、牙周指标[牙龈指数(GI)、牙菌斑指数(PLI)、牙周探诊深度(PD)]、龈沟液炎症因子[超敏C反应蛋白(hs-CRP)、肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)]水平、口腔变形链球菌菌落计数。结果观察组患儿总有效率93.94%高于对照组的75.76%,差异具有统计学意义(P<0.05)。观察组患儿术中疼痛敏感程度0级、1级、2级、3级比例分别为81.82%(54/66)、12.12%(8/66)、6.06%(4/66)、0,对照组分别为63.64%(42/66)、15.15%(10/66)、9.09%(6/66)、12.12%(8/66);观察组患儿术中疼痛敏感程度低于对照组,差异具有统计学意义(P<0.05)。两组患儿GI、PLI、PD治疗前后组内、组间比较,差异无统计学意义(P>0.05)。治疗后,观察组患儿数字模拟评分法(NRS)评分(2.91±0.43)分低于治疗前的(7.14±1.32)分;对照组患儿NRS评分(4.62±1.14)分低于治疗前的(7.15±1.30)分;观察组患儿NRS评分低于对照组,差异具有统计学意义(P<0.05)。治疗后,观察组患儿龈沟液hs-CRP(7.08±1.20)mg/L、TNF-α(3.11±0.80)ng/ml、IL-6(1.90±0.30)ng/ml均高于治疗前的(6.50±1.27)mg/L、(2.71±0.40)ng/ml、(1.10±0.21)ng/ml,口腔变形链球菌菌落计数(4.02±0.75)lg10CFU/ml低于治疗前的(5.02±0.53)lg10CFU/ml;对照组患儿龈沟液hs-CRP(7.90±1.17)mg/L、TNF-α(3.81±0.83)ng/ml、IL-6(2.48±0.31)ng/ml均高于治疗前的(6.55±1.22)mg/L、(2.69±0.42)ng/ml、(1.11±0.20)ng/ml,口腔变形链球菌菌落计数(4.62±0.41)lg10CFU/ml低于治疗前的(5.02±0.62)lg10CFU/ml;观察组患儿龈沟液hs-CRP、TNF-α、IL-6水平及口腔�Objective To investigate the clinical efficacy of carisolv chemo-mechanical caries removal technique in the treatment of caries.Methods A total of 132 children with dental caries were randomly divided into observation group and control group,with 66 cases in each group.The control group was treated with conventional drill grinding,while the observation group was treated with carisolv chemo-mechanical caries removal technique.Both groups were compared in terms of therapeutic effect,intraoperative pain sensitivity,filling effect,proportion of filling area,filling time,treatment time,parental satisfaction,pain degree,periodontal indexes[gingival index(GI),plaque index(PLI),probing depth(PD)],gingival crevicular fluid inflammatory factors[high-sensitivity C-reactive protein(hs-CRP),tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)]level,Streptococcus mutans count in the oral cavity before and after treatment.Results The total effective rate 93.94% in the observation group was higher than 75.76% in the control group,and the difference was statistically significant(P<0.05).In the observation group,the proportions of intraoperative pain sensitivity grades 0,1,2,and 3 were 81.82%(54/66),12.12%(8/66),6.06%(4/66),and 0,and those in the control group were 63.64%(42/66),15.15%(10/66),9.09%(6/66),and 12.12%(8/66);the intraoperative pain sensitivity of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).Before and after treatment,there was no statistically significant difference in GI,PLI and PD within and between the two groups(P>0.05).After treatment,the numerical rating scale(NRS)score(2.91±0.43)points of observation group was lower than(7.14±1.32)points before treatment;the NRS score(4.62±1.14)points of the control group was lower than(7.15±1.30)points before treatment;the NRS score of the observation group was lower than that of the control group;all the differences were statistically significant(P<0.05).After treatment,the levels of hs-CRP(7.08±1

关 键 词：伢典微创凝胶去龋技术 龋齿 牙钻磨牙技术 

分 类 号：R781.1[医药卫生—口腔医学]