The development of molecular and nano actinide decorporation agents  

作　　者：Xiaomei Wang Cen Shi Jingwen Guan Yemeng Chen Yigong Xu Juan Diwu Shuao Wang 

机构地区：[1]State Key Laboratory of Radiation Medicine and Protection,School for Radiological and Interdisciplinary Sciences(RAD-X)and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions,Soochow University,Suzhou 215123,China

出　　处：《Chinese Chemical Letters》2022年第7期3395-3404,共10页中国化学快报（英文版）

基　　金：supported by grants from the National Natural Science Foundation of China(Nos.21976127,U2167222,21790370,22106116);the Natural Science Foundation of Jiangsu Province(No.BK20190044,BK20210736);funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);China Postdoctoral Science Foundation(No.2020M681716)。

摘　　要：Internal contamination of actinides has led to significant health hazards to the public and workers in the context of nuclear power plant accidents,uranium ore mining,and reprocessing of the used fuel.An effective sequestering agent that is able to remove accidentally incorporated actinides in vivo with low toxicity is always in urgent need.The molecular decorporation ligands have been the most widely researched agents for the past few decades,while preliminary studies of functionalized nanoparticles have shown their clear advantages in metal binding selectivity,toxicity,and oxidative stress alleviation.Herein,the state-of-the-art of those two types of decorporation agents is presented with special attention being paid on the correlation between the solution and solid-state chemistry of those agents with actinides and the corresponding decorporation efficacies.

关 键 词：ACTINIDES CHELATOR Binding selectivity Coordination mode Decorporation efficiency 

分 类 号：TB383.1[一般工业技术—材料科学与工程]