CHELATOR

作品数：25被引量：37H指数：3
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相关领域：医药卫生生物学更多>>
相关作者：焦举陈小夏何冰邹琼陈一岳更多>>
相关机构：中山大学附属第三医院广东药学院河北工业大学四川大学更多>>
相关期刊：《Chinese Medical Journal》《Chinese Journal of Cancer Research》《Asian Pacific Journal of Tropical Biomedicine》《Chinese Journal of Chemistry》更多>>
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Wilson's disease in two siblings from Ecuador:Two case reports
《World Journal of Clinical Cases》2025年第3期50-60,共11页Enrique Carrera Jonathan Alvarado Martina Astudillo Galo Pillajo 
BACKGROUND Wilson's disease(WD)is a rare metabolic disorder of copper accumulation in organs such as liver,brain,and cornea.Diagnoses and treatments are challenging in settings,where advanced diagnostic tests are unav...
关键词：Wilson disease Kayser-Fleischer rings Copper chelator D-PENICILLAMINE Trientine tetrahydrochloride Case report 
Molecularly Imprinted Porous-Organic Framework with pH-Responsive Adsorption Sites for the Selective Adsorption of Iron
《Chinese Journal of Chemistry》2024年第24期3324-3330,共7页Yajie Yang Fuli Cai Cheng Zhang Nan Gao Suming Zhang Guangtong Wang Ye Yuan 
supported by the National Key R&D Program of China(Grant No.2022YFB3805902);the National Natural Science Foundation of China(Grant Nos.22322501,52204389,21975039,and 22077118);the Fundamental Research Funds for the Central Universities,Excellent Youth Team Program(grant No.2412023YQ001);the China Postdoctoral Science Foundation(2023T160261);the Finance Special Project on Medical and Health Talents of the Finance Department of Jilin Province(JLSWSRCZX2023-52);WBE Liver Fibrosis Foundation(No.2020009);Jilin Province Science and Technology Development Plan Project(YDZJ202401202ZYTS).
Regulating brain iron metabolism and reducing neuronal ferroptosis is proven to be a potential method for treating Alzheimer's disease(AD).However,gastric juice has a pH of 1.1—2.2 where a large number of interfering...
关键词：Alzheimer's disease Ferroptosis PH-RESPONSIVE Porous chelator Iron ion POLYANION Adsorption Hydrogen bonds 
Successful treatment of acute liver failure due to Wilson’s disease: Serendipity or fortuity?
《World Journal of Hepatology》2024年第8期1111-1119,共9页Valeria Delle Cave Fabiola Di Dato Pier Luigi Calvo Maria Immacolata Spagnuolo Raffaele Iorio 
BACKGROUND Acute liver failure(ALF)may be the first and most dramatic presentation of Wilson’s disease(WD).ALF due to WD(WD-ALF)is difficult to distinguish from other causes of liver disease and is a clear indication...
关键词：Fulminant liver failure Copper CHELATOR Zinc STEROIDS Liver transplantation Autoimmune hepatitis Prognostic score 24 hour-urinary copper excretion Native liver 
Chelator-Free法标记介孔二氧化硅纳米颗粒用于乳腺癌靶向PET成像被引量：1
《解剖学研究》2023年第2期157-163,共7页张桂铃 邹睿 陈光锋 谢艳萍 帅永康 邹琼 焦举 
中山大学附属第三医院国家自然科学基金培育项目(2021GZRPYQN03);广东省自然科学基金项目(2023A1515011362)。
目的 使用Chelator-Free法进行^(68)Ga标记介孔二氧化硅纳米颗粒(MSNs),制备新型正电子发射计算机断层显像(PET)分子探针,并检测其表征、生物安全性、放射性化学性能、体内生物分布及评估其体内乳腺癌靶向PET成像性能。方法 用模板法合...
关键词：乳腺癌 介孔二氧化硅纳米颗粒 分子探针 PET成像 
Multiple effects of polydopamine nanoparticles on Cu^(2+)-mediated Alzheimer's β-amyloid aggregation被引量：1
《Chinese Journal of Chemical Engineering》2023年第2期144-152,共9页Xueqing Chen Weiqun Gao Yan Sun Xiaoyan Dong 
funded by the National Natural Science Foundation of China (21978207 and 21621004);the Natural Science Foundation of Tianjin from Tianjin Municipal Science and Technology Commission (19JCZDJC36800)。
Deposition of β-amyloid protein(Aβ) is the main hallmark of Alzheimer's disease(AD), and it has been well recognized that Cu^(2+)-mediated Aβ aggregation plays a crucial role in AD pathological processes.Cu^(2+)bin...
关键词：Protein AGGREGATION NANOPARTICLES Photothermal therapy Reactive oxygen species Cu^(2+)chelator 
The development of molecular and nano actinide decorporation agents被引量：2
《Chinese Chemical Letters》2022年第7期3395-3404,共10页Xiaomei Wang Cen Shi Jingwen Guan Yemeng Chen Yigong Xu Juan Diwu Shuao Wang 
supported by grants from the National Natural Science Foundation of China(Nos.21976127,U2167222,21790370,22106116);the Natural Science Foundation of Jiangsu Province(No.BK20190044,BK20210736);funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);China Postdoctoral Science Foundation(No.2020M681716)。
Internal contamination of actinides has led to significant health hazards to the public and workers in the context of nuclear power plant accidents,uranium ore mining,and reprocessing of the used fuel.An effective seq...
关键词：ACTINIDES CHELATOR Binding selectivity Coordination mode Decorporation efficiency 
Compounded chelating agent derived from fruit residue extracts effectively enhances Cd phytoextraction by Sedum alfredii被引量：2
《Soil Ecology Letters》2021年第3期253-265,共13页Jipeng Luo Jiabin Liang Yuchao Song Xinyu Guo Youzheng Ning Nanlin Liu Heping Zhao Tingqiang Li 
the National Natural Science Foundation of China(41671315,41977107);National Postdoctoral Program for Innovative Talents(BX20200293);Zhejiang Provincial Natural Science Foundation of China(LZ18D010001);National Key Research and Development Project of China(2016YFD0800802);the Fundamental Research Funds for the Central Universities,China's Agriculture Research System(CARS-04);Fundamental Research Funds for the Central Universities(2020FZZX001-06).
Chelating agent is known as the enhancer for metal phytoextraction;however,there is still a lack of efficient and environmentally sustainable chelators.Here,lemon residue extraction(LRE),prepared from 11 kinds of frui...
关键词：Compounded plant-derived chelator Fruit residue Cadmium PHYTOEXTRACTION Sedum alfredii 
Wilson's disease:Revisiting an old friend被引量：10
《World Journal of Hepatology》2021年第6期634-649,共16页Ana Lucena-Valera Domingo Perez-Palacios Rocio Muñoz-Hernandez Manuel Romero-Gómez Javier Ampuero 
Consejería de Salud.Junta de Andalucía,No.PI_0039_2017;Junta de andalucia,No.201799903406796.
Wilson's disease(WD)is a rare condition caused by copper accumulation primarily in the liver and secondly in other organs,such as the central nervous system.It is a hereditary autosomal recessive disease caused by a d...
关键词：Wilson´s disease Copper ATP7B CERULOPLASMIN CHELATOR Liver disease 
A new iron(Ⅲ) chelator of coprogen-type siderophore from the deep-sea-derived fungus Mycosphaerella sp. SCSIO z059被引量：2
《Chinese Journal of Natural Medicines》2020年第4期243-249,共7页HUANG Zhong-Hui LIANG Xiao QI Shu-Hua 
the Guangdong Provincial-level Special Funds for Promoting High-quality Economic Development (No. 2020032);Natural science foundation of Guangdong province (No. 2017A030313235);Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)(No. GML2019-ZD0406);National Natural Science Foundation of China (No.81673326).
Mycosphazine A(1), a new iron(Ⅲ) chelator of coprogen-type siderophore, and mycosphamide A(2), a new cyclic amide benzoate, together with six known aryl amides(3-8), were isolated from the fermentation broth of the d...
关键词：Deep-sea-derived fungus Mycosphaerella sp Iron(Ⅲ)chelator Coprogen-type siderophore Cyclic amide Biofilm formation 
Selective Extraction of Light Lanthanides by N,N-di(2-ethylhexyl)-diglycolamic Acid:Comparative Study with N,N-dimethyl-diglycolamic Acid as Chelator in Aqueous Solution被引量：3
《Annual Report of China Institute of Atomic Energy》2019年第1期141-142,共2页YANG Suliang SHERIF MIbrahim ZHANG Yan XUE Yun MA Fuqiu GAO Yang ZHOU Yu TIAN Guoxin 
The complexation and selectivity of N,Ndi(2-ethylhexyl)-diglycolamic acid(HDEHDGA,HA)/kerosene toward the light lanthanides,La(Ⅲ),Ce(Ⅲ),Pr(Ⅲ),and Nd(Ⅲ),are presented for the extraction from chloride media.In the l...
关键词：ethylhexyl GLYCOL lanthanide 
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