八珍汤加减辅助西药治疗慢性牙周炎临床研究  

Clinical Study on Modified Bazhen Tang Assisting Western Medicine for Chronic Periodontitis

作　　者：郑俊杰 ZHENG Junjie

机构地区：[1]余姚市中医医院口腔科,浙江余姚315400

出　　处：《新中医》2022年第13期20-23,共4页New Chinese Medicine

摘　　要：目的:观察八珍汤加减辅助西药治疗慢性牙周炎的临床疗效。方法:选择136例慢性牙周炎患者,按随机数字表法分为对照组和观察组各68例。2组均进行口腔卫生指导,并给予牙周基础治疗,对照组在牙周基础治疗后予以甲硝唑片口服,观察组在对照组基础上给予八珍汤加减口服。评价2组临床疗效,比较2组牙周指标[菌斑指数(PLI)、牙周袋深度(PD)、牙龈指数(GI)、附着丧失(AL)]、中医证候评分及不良反应发生率。结果:观察组总有效率为91.18%,高于对照组77.94%,差异有统计学意义(P<0.05)。治疗前,2组PLI、PD、GI、AL比较,差异无统计学意义(P>0.05)。治疗后,2组PLI、PD、GI、AL较治疗前降低,且观察组PLI、PD、GI、AL均低于对照组,差异均有统计学意义(P<0.05)。治疗前,2组牙龈红肿、牙龈出血、牙齿松动、口臭评分比较,差异无统计学意义(P>0.05)。治疗后,2组牙龈红肿、牙龈出血、牙齿松动、口臭评分较治疗前降低,且观察组各项评分均低于对照组,差异均有统计学意义(P<0.05)。观察组不良反应总发生率为4.41%,低于对照组17.65%,差异有统计学意义(P<0.05)。结论:八珍汤加减辅助西药治疗慢性牙周炎能显著改善牙周指标,减轻临床症状,不良反应少。Objective:To observe the clinical effect of modified Bazhen tang assisting western medicine for chronic periodontitis.Methods:A total of 136 cases of patients with chronic periodontitis were selected and divided into the control group and the observation group according to the random number table method,with 68 cases in each group.Both groups were given oral hygiene instruction and periodontal basic treatment.After being given periodontal basic treatment,the control group was additionally given the oral administration of metronidazole tablets,and the observation group was additionally given the oral administration of modified Bazhen tang based on the treatment of the control group.The clinical effects in the two groups were evaluated;the periodontal indexes including plaque index(PLI),periodontal pocket depth(PD),gingival index(GI)and attachment loss(AL),Chinese medicine symptom scores and incidences of adverse reactions in the two groups were compared.Results:The total effective rate was 91.18%in the observation group,higher than that of 77.94%in the control group,the difference being significant(P<0.05).Before treatment,there was no significant difference being found in the comparison of PLI,PD,GI and AL between the two groups(P>0.05).After treatment,PLI,PD,GI and AL in the two groups were decreased when compared with those before treatment,and PLI,PD,GI and AL in the observation group were lower than those in the control group,differences being significant(P<0.05).Before treatment,there was no significant difference being found in the comparison of the scores of gingival redness and swelling,gingival bleeding,tooth mobility and halitosis between the two groups(P>0.05).After treatment,the scores of gingival redness and swelling,gingival bleeding,tooth mobility and halitosis in the two groups were decreased when compared with those before treatment,and the above scores in the observation group were lower than those in the control group,differences being significant(P<0.05).The total incidence of adverse reaction

关 键 词：慢性牙周炎 八珍汤 甲硝唑 牙周指标 中医证候评分 不良反应发生率 

分 类 号：R781.4[医药卫生—口腔医学]