基于GMPE模块OCT与眼底彩色照相法测量客观眼球旋转度的比较  

Comparison of the objective ocular torsion measured with GMPE module-based OCT and fundus color photography

作　　者：李娜敏 郭长梅 张璐 赵润泽 张桂鸥 朱锦婷 孙董洁 惠延年 窦国睿 Na-Min Li;Chang-Mei Guo;Lu Zhang;Run-Ze Zhao;Gui-Ou Zhang;Jin-Ting Zhu;Dong-Jie Sun;Yan-Nian Hui;Guo-Rui Dou(Department of Ophthalmology,Xijing Hospital,Air Force Military Medical University,Xi’an 710032,Shaanxi Province,China)

机构地区：[1]空军军医大学西京医院眼科,陕西省西安市710032

出　　处：《国际眼科杂志》2022年第8期1396-1401,共6页International Eye Science

基　　金：陕西省自然科学基础研究计划重点项目(No.2021JZ-30);空军军医大学第一附属医院学科助推计划多学科综合诊疗项目(No.XJZT19MDT12);空军军医大学第一附属医院学科助推计划临床研究类(No.XJZT19ML19)。

摘　　要：目的:比较基于GMPE模块光学相干断层扫描(OCT)与传统眼底彩色照相法(FCP)测量客观眼球旋转度的一致性和可行性。方法:纳入2020-12/2021-03我院斜弱视门诊受检者,同一天用基于GMPE模块OCT与FCP两种方法测量客观眼球旋转度。FCP使用Adobe Photoshop软件手动定位测量黄斑中心凹-视盘中心夹角度数(FDA),基于GMPE模块OCT软件自动定位黄斑和视盘中心测量FDA。结果:纳入55例受检者,OCT测量FDA分别为右-6.6°±4.5°和左-8.8°±4.7°,FCP测量FDA分别为右-6.6°±4.7°和左-8.4°±4.1°,两种方法测量结果无差异(P_(右眼)=0.90,P_(左眼)=0.08)。外斜视患者OCT测量FDA分别为右-5.8°±4.9°和左-9.1°±4.5°,FCP测量FDA分别为右-5.7°±5.0°和左-8.6°±4.3°(P_(右眼)=0.75,P_(左眼)=0.15)。类似地,内斜视患者OCT测量FDA分别为右-9.0°±7.3°和左-11.3°±3.5°,而FCP测量FDA分别为右-10.0°±7.0°和左-10.1°±2.8°(P_(右眼)=0.21,P_(左眼)=0.10),两种测量方法在内外斜视患者中均无差异(P>0.05)。Pearson检验及Bland-Altman分析两种方法的结果高度相关一致(r_(右眼)=0.93,r_(左眼)=0.94,均P<0.01)。结论:基于GMPE模块OCT可用于客观眼球旋转度的测量,且可信度及重复度高,临床有望替代眼底彩色照相法。AIM:To compare the consistency and feasibility of objective ocular torsion measured with GMPE module-based optical coherence tomography(OCT)and fundus color photography(FCP).METHODS:Patients were enrolled in our strabismus clinic from December 2020 to March 2021,and the objective ocular torsion of the eyes was measured by both GMPE module-based OCT and FCP on the same day.FCP was used to measure the fovea-disc angle(FDA)manually by using the Adobe Photoshop software,while the GMPE module-based OCT software positioned automatically the macula and the center of the optic disc to measure the FDA.RESULTS:Fifty-five patients were included,the FDA measured by OCT was-6.6°±4.5°in the right eye and-8.8°±4.7°in the left eye,respectively;The FDA measured by FCP was-6.6°±4.7°in the right eye and-8.4°±4.1°in the left eye,respectively,with no statistically significant difference between the results of the two methods(P_(right eye)=0.90,P_(left eye)=0.08).In patients with exotropia,the FDA measured by OCT was-5.8°±4.9°in the right eye and-9.1°±4.5°in the left eye,respectively,the FDA measured by FCP was-5.7°±5.0°in the right eye and-8.6°±4.3°in the left eye,respectively,(P_(right eye)=0.75,P_(left eye)=0.15).Similarly,the patients with esotropia,the FDA measured by OCT was-9.0°±7.3°in the right eye and-11.3°±3.5°in the left eye,respectively,while the FDA measured by FCP was-10.0°±7.0°in the right and-10.1°±2.8°in the left eye(P_(right eye)=0.21,P_(left eye)=0.10),respectively.There were no significant differences between the two methods in patients with esotropia or exotropia(P>0.05).The results of both Pearson test and Bland-Altman analysis were highly correlated(r_(right eye)=0.93,r_(left eye)=0.94,P<0.01).CONCLUSION:GMPE module-based OCT can be used for objective ocular torsion measurement with high reliability and reproducibility,and is a promising clinical alternative to the fundus color photographic method.

关 键 词：客观眼球旋转度 光学相干断层扫描(OCT) 眼底彩色照相 Adobe Photoshop软件 

分 类 号：R770.4[医药卫生—眼科]