非综合征唇腭裂患者与骨性Ⅰ类人群的上气道对称性分析研究  

Analysis of upper airway symmetry between patients with non-syndromic cleft lip and palate and skeletal ClassⅠ

作　　者：苏咏宽 潘永初[2] 李媛 罗瑶 侯伟 韩霖霏 SU Yongkuan;PAN Yongchu;LI Yuan;LUO Yao;HOU Wei;HAN Linfei(Department of Stomatology,Affiliated Taikang Xianlin Drum Tower Hospital,Medical School of Nanjing University,Nanjing 210046,China)

机构地区：[1]南京大学医学院附属泰康仙林鼓楼医院口腔科,江苏南京210046 [2]南京医科大学口腔疾病研究江苏省重点实验室,南京医科大学附属口腔医院正畸科,江苏南京210029 [3]南京医科大学附属口腔医院第三门诊部,江苏南京210029

出　　处：《口腔医学》2022年第7期617-621,共5页Stomatology

基　　金：国家自然科学基金(81970969)。

摘　　要：目的对非综合征唇腭裂患者与骨性Ⅰ类人群的上气道对称性进行三维分析对比研究。方法选择非综合征唇腭裂患者51例(男性37例,女性14例,平均年龄(17.40±5.93)岁)和骨性Ⅰ类人群53例(男39例,女14例,平均年龄(17.40±6.07)岁),拍摄锥形束CT,应用Dolphin 3D 11.9软件进行三维测量分析,采用SPSS 25.0软件包进行独立样本t检验对比两者上气道对称性。结果单侧唇腭裂患者上气道鼻咽段和腭咽段为不对称结构(P<0.05),其患侧横截面直径小于健侧;而双侧唇腭裂患者及骨性Ⅰ类人群,其上气道鼻咽和腭咽段为基本对称结构(P>0.05)。结论单侧唇腭裂患者的上气道横截面直径中,有患侧偏向健侧的趋势,应注重其患侧的通气及呼吸情况。Objective To conduct a three-dimensional comparative study on upper airway symmetry between patients with non-syndromic cleft lip and palate and populations with skeletal ClassⅠ.Methods Fifty-one cases of non-syndromic cleft lip and palate patients(37 males,14 females,average age(17.40±5.93)years)and 53 cases of skeletal ClassⅠpopulations(39 males,14 females,average age(17.40±6.07)years)were included.Cone-beam CT was taken,and Dolphin 3 D 11.9 software was used for three-dimensional measurement and analysis.SPSS 25.0 software package was used for independent sample t-test to conduct the analysis of upper airway symmetry.Results The nasopharyngeal and velopharyngeal segments of the upper airway in patients with unilateral cleft lip and palate were asymmetrical structures(P<0.05),and the cross-sectional diameter of the affected side was smaller than that of the healthy side;while the patients with bilateral cleft lip and palate and skeletal ClassⅠpopulations had an asymmetric structure(P<0.05).The nasopharyngeal and velopharyngeal segments of the upper airway were basically symmetrical(P<0.05).Conclusion In the cross-sectional diameter of the upper airway in patients with unilateral cleft lip and palate,the affected side tends to be biased toward the healthy side,and attention should be paid to the ventilation and respiration of the affected side of cleft lip and palate.

关 键 词：非综合征唇腭裂 锥形束CT 上气道对称性 

分 类 号：R783.5[医药卫生—口腔医学]