前列腺腺癌转化为神经内分泌肿瘤1例报道并文献复习  

A case report and literature review prostatic adenocarcinoma transformed into neuroendocrine tumor of the prostate

作　　者：尹竺晟 梁新军[1] YIN Zhucheng;LIANG Xinjun(Department of Medical Oncology,Hubei Cancer Hospital,Hubei Province,Wuhan430000,China)

机构地区：[1]湖北省肿瘤医院腹部肿瘤内科,湖北武汉430000

出　　处：《中国医药导报》2022年第21期185-188,共4页China Medical Herald

基　　金：国家自然科学基金资助项目(81772499)。

摘　　要：前列腺神经内分泌肿瘤是一种罕见的恶性肿瘤。为了提高对前列腺神经内分泌肿瘤的认识,本研究回顾性分析湖北省肿瘤医院收治的1例前列腺腺癌转化为神经内分泌肿瘤患者资料。结合相关文献复习前列腺神经内分泌肿瘤的临床、病理特征、诊疗方法及预后。前列腺神经内分泌肿瘤临床罕见,部分为前列腺腺癌雄激素剥夺治疗后转化为神经内分泌肿瘤,确诊依据临床及病理诊断,前列腺神经内分泌肿瘤恶性程度高,治疗以化疗为主,预后差。Neuroendocrine tumor of the prostate is a rare malignant tumor.In order to improve the understanding of neuroendocrine tumor of the prostate,this study retrospectively analyzed the data of one case of prostate adenocarcinoma transformed into neuroendocrine tumor of the prostate in Hubei Cancer Hospital.The clinical and pathological features,diagnosis,and treatment and prognosis of neuroendocrine tumor of the prostate were reviewed in combination with relevant literature.Neuroendocrine tumor of the prostate is rare,and some of them are prostate adenocarcinoma transformed into neuroendocrine tumor after androgen deprivation therapy.The diagnosis is based on clinical and pathological diagnosis.Neuroendocrine tumor of the prostate has a high degree of malignancy.The treatment is mainly chemotherapy,and the prognosis is poor.

关 键 词：前列腺腺癌 前列腺神经内分泌肿瘤 雄激素剥夺治疗 转化 

分 类 号：R73[医药卫生—肿瘤]